Mip^Cts
Spontaneous Allele Detail

Summary

• Symbol: Mip^Cts
• Name: major intrinsic protein of lens fiber; cataract and small eye
• MGI ID: MGI:1860482
• Synonyms: cataract Shionogi, cs
• Gene: Mip Location: Chr10:128061707-128067681 bp, + strand Genetic Position: Chr10, 76.49 cM, cytoband D1
• Alliance: Mip^Cts page

Mutation origin

• Strain of Origin: Jcl:ICR

Mutation description

• Allele Type: Spontaneous
• Mutation: Single point mutation
• Mutation details: This spontaneous mutation is a C-to-T transition in exon 2 results in a leucine to phenylalanine mutation at amino acid 168 (p.L168F). (J:196356)
• Inheritance: Semidominant

Disease models

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Mip Mutation: 31 strains or lines available

References

• Original: J:24627 Ohotori H, et al., Small Eye and Cataract, a new dominant mutation in the mouse. Jikken Dobutsu. 1968;17(3):91-6
• All: 5 reference(s)