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Srydl1Rlb
Spontaneous Allele Detail
Summary
Symbol: Srydl1Rlb
Name: sex determining region of Chr Y; sex determining region of Chr Y-deletion 1, Robin Lovell-Badge
MGI ID: MGI:1857786
Synonyms: Srydl1Rob, Srym1, Tdym1, Y-, Yq-del, YTdym1
Gene: Sry  Location: ChrY:2662471-2663658 bp, - strand  Genetic Position: ChrY, cytoband p
Alliance: Srydl1Rlb page
Mutation
origin
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Spontaneous
Mutation:    Intragenic deletion
 
Mutation detailsThis allele contains an 11 kb deletion in the testis-determining region of the gene, including a highly conserved exon encoding the HMG box domain. (J:2258)
Inheritance:    Semidominant
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 33 assay results
1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Sry Mutation:  51 strains or lines available
References
Original:  J:10734 Lovell-Badge R, et al., XY female mice resulting from a heritable mutation in the primary testis-determining gene, Tdy. Development. 1990 Jul;109(3):635-46
All:  73 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory