Grpr^tm1Jfb
Targeted Allele Detail

Summary

• Symbol: Grpr^tm1Jfb
• Name: gastrin releasing peptide receptor; targeted mutation 1, James F Battey
• MGI ID: MGI:1857462
• Synonyms: GRP-R-, GRPR^-
• Gene: Grpr Location: ChrX:162296900-162332673 bp, - strand Genetic Position: ChrX, 75.63 cM
• Alliance: Grpr^tm1Jfb page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:46897
• Parent Cell Line: RW-4 (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• A neomycin resistance cassette disrupted exon 1 of the gene. (J:46897)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Grpr Mutation: 14 strains or lines available

References

• Original: J:46897 Hampton LL, et al., Loss of bombesin-induced feeding suppression in gastrin-releasing peptide receptor-deficient mice. Proc Natl Acad Sci U S A. 1998 Mar 17;95(6):3188-92
• All: 25 reference(s)