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Gene Expression Data
Assay Details
Assay
Reference: J:344365 Abad C, et al., Gatad2b, associated with the neurodevelopmental syndrome GAND, plays a critical role in neurodevelopment and cortical patterning. Transl Psychiatry. 2024 Jan 18;14(1):33
Assay type: Immunohistochemistry
MGI Accession ID: MGI:8400450
Gene symbol: Tbr1
Gene name: T-box brain transcription factor 1
Antibody: anti-Tbr1 (ab31940)
Detection system: Secondary antibody
Results
Specimen 4B +/+: embryonic day 16.5 (more )
Note: Triple labeled: blue - Tbr1; red - Bcl11b (assay MGI:8400449); green - Satb2 (assay MGI:8400448).
Structure Level Pattern Image Note
TS24: neocortex Present Regionally restricted 4B +/+ Highly expressed in layer VI.
Specimen 4B stop/+: embryonic day 16.5; Gatad2btm1a(EUCOMM)Hmgu/Gatad2b+ (more )
Note: Triple labeled: blue - Tbr1; red - Bcl11b (assay MGI:8400449); green - Satb2 (assay MGI:8400448).
Structure Level Pattern Image Note
TS24: neocortex Present Regionally restricted 4B stop/+ Proportion of expressing cells vo-expressing Bcl11b in layer V significantly higher compared to wild type.
Specimen 4B stop/stop: embryonic day 16.5; Gatad2btm1a(EUCOMM)Hmgu/Gatad2btm1a(EUCOMM)Hmgu (more )
Note: Triple labeled: blue - Tbr1; red - Bcl11b (assay MGI:8400449); green - Satb2 (assay MGI:8400448).
Structure Level Pattern Image Note
TS24: neocortex Present Regionally restricted 4B stop/stop Proportion of expressing cells vo-expressing Bcl11b in layer V significantly higher compared to wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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10/06/2026
MGI 6.29 		The Jackson Laboratory