Neurog3 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:279716 Braitsch CM, et al., LATS1/2 suppress NFkappaB and aberrant EMT initiation to permit pancreatic progenitor differentiation. PLoS Biol. 2019 Jul;17(7):e3000382
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:8351681
Gene symbol:	Neurog3
Gene name:	neurogenin 3

Antibody:	anti-Ngn3 (clone F25A1B3)
Detection system:	Secondary antibody coupled to Alexa Fluor

Results

S3A WT lower ©

Specimen S3A WT: embryonic day 10.75 (more

)
Note: Controls were either wild type or heterozygous littermates. Double labeled: red - Neurog3; green - Prox1 (assay MGI:8351679).

Structure	Level	Pattern	Image	Note
TS17: pancreas primordium	Present		S3A WT lower

Specimen S3A Lats1/2^PanKO: embryonic day 10.75; Lats1^tm1.1Jfm/Lats1^tm1.1Jfm, Lats2^tm1.1Jfm/Lats2^tm1.1Jfm, Tg(Pdx1-cre)89.1Dam/0 (more

)
Note: Conditional mutant. Double labeled: red - Neurog3; green - Prox1 (assay MGI:8351679).

Structure	Level	Pattern	Image	Note
TS17: pancreas primordium	Weak		S3A Lats1/2^PanKO lower	The proportion of NEUROG3+ cells was significantly lower in Lats1/2<PanKO> pancreas.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 10/06/2026 MGI 6.29