Prox1 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:279716 Braitsch CM, et al., LATS1/2 suppress NFkappaB and aberrant EMT initiation to permit pancreatic progenitor differentiation. PLoS Biol. 2019 Jul;17(7):e3000382
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:8351679
Gene symbol:	Prox1
Gene name:	prospero homeobox 1

Antibody:	anti-Prox1
Detection system:	Secondary antibody coupled to Alexa Fluor

Results

S3A WT lower ©

Specimen S3A WT: embryonic day 10.75 (more

)
Note: Controls were either wild type or heterozygous littermates. Double labeled: green - Prox1; red - Neurog3 (assay MGI:8351681).

Structure	Level	Pattern	Image	Note
TS17: pancreas primordium	Present	Regionally restricted	S3A WT lower	Expression was detected in epithelium.

Specimen S3A Lats1/2^PanKO: embryonic day 10.75; Lats1^tm1.1Jfm/Lats1^tm1.1Jfm, Lats2^tm1.1Jfm/Lats2^tm1.1Jfm, Tg(Pdx1-cre)89.1Dam/0 (more

)
Note: Conditional mutant. Double labeled: green - Prox1; red - Neurog3 (assay MGI:8351681).

Structure	Level	Pattern	Image	Note
TS17: pancreas primordium	Present	Regionally restricted	S3A Lats1/2^PanKO lower	No significant difference in the relative percentage of immunopositive epithelial cells was found between WT and mutant tissue at E10.75.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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