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Gene Expression Data
Assay Details
Assay
Reference: J:279716 Braitsch CM, et al., LATS1/2 suppress NFkappaB and aberrant EMT initiation to permit pancreatic progenitor differentiation. PLoS Biol. 2019 Jul;17(7):e3000382
Assay type: Immunohistochemistry
MGI Accession ID: MGI:8347770
Gene symbol: Yap1
Gene name: yes-associated protein 1
Antibody: Anti-Phosph-Yap (4911)
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 1M: embryonic day 12.5 (more )
Note: Controls were either wild type or heterozygous littermates. Triple labeled: green - Yap1; white - Cdh1 (assay MGI:8346384); red - Gcg (assay MGI:8346997).
Structure Level Pattern Image Note
TS20: pancreas Present 1M left , 1M right
Specimen 1N: embryonic day 12.5; Lats1tm1.1Jfm/Lats1tm1.1Jfm, Lats2tm1.1Jfm/Lats2tm1.1Jfm, Tg(Pdx1-cre)89.1Dam/0 (more )
Note: Conditional mutant. Triple labeled: green - Yap1; white - Cdh1 (assay MGI:8346384); red - Gcg (assay MGI:8346997).
Structure Level Pattern Image Note
TS20: pancreas Absent 1N right , 1N left
Specimen 1O: embryonic day 12.5; Lats1tm1.1Jfm/Lats1tm1.1Jfm, Lats2tm1.1Jfm/Lats2tm1.1Jfm, Tg(Pdx1-cre)89.1Dam/0, Wwtr1tm1.1Eno/Wwtr1+, Yap1tm1.1Eno/Yap1tm1.1Eno (more )
Note: Conditional mutant. Triple labeled: green - Yap1; white - Cdh1 (assay MGI:8346384); red - Gcg (assay MGI:8346997).
Structure Level Pattern Image Note
TS20: pancreas Absent 1O right , 1O left
Specimen S1G: embryonic day 10.75 (more )
Note: Controls were either wild type or heterozygous littermates.
Structure Level Pattern Image Note
TS17: pancreas primordium Present S1G right , S1G left In WT pancreas cytoplasmic pYAP1 was present.
Specimen S1I: embryonic day 10.75; Lats1tm1.1Jfm/Lats1tm1.1Jfm, Lats2tm1.1Jfm/Lats2tm1.1Jfm, Tg(Pdx1-cre)89.1Dam/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: pancreas primordium Absent S1I right , S1I left Cytoplasmic Yap1 expression was lost.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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10/06/2026
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