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Gene Expression Data
Assay Details
Assay
Reference: J:365383 Short KL, et al., Disrupted glucocorticoid receptor cell signalling causes a ciliogenesis defect in the fetal mouse renal tubule. EMBO Rep. 2025 Apr 17;
Assay type: Immunohistochemistry
MGI Accession ID: MGI:8262654
Gene symbol: Nr3c1
Gene name: nuclear receptor subfamily 3, group C, member 1
Results
Specimen 1H GR (1): embryonic day 18.5 (more )
Note: Double labeled: red - Nr3c1; green - DBA.
Structure Level Pattern Image Note
TS26: collecting duct Present 1H (1) Expression localized to collecting ducts.
Specimen 1H GR (2): embryonic day 18.5 (more )
Note: Double labeled: red - Nr3c1; green - LTL.
Structure Level Pattern Image Note
TS26: renal proximal tubule Present 1H (2) Expression localized to proximal tubules.
Specimen 1H GR (3): embryonic day 18.5 (more )
Note: Double labeled: red - Nr3c1; green - Meis1 (assay MGI:8262657) and Meis2 (assay MGI:8262668) and Meis3 (assay MGI:8262669).
Structure Level Pattern Image Note
TS26: renal interstitium Present 1H (3) Expression localized to stroma.
Specimen 1H GR (4): embryonic day 18.5 (more )
Note: Double labeled: red - Nr3c1; green - Nphs1 (assay MGI:8262658).
Structure Cell Type Level Pattern Image Note
TS26: glomerular tuft metanephric podocyte Present 1H (4) Expression localized to podocytes.
Specimen S1A E14.5 GR: embryonic day 14.5 (more )
Note: Double labeled: red - Nr3c1; green - LTL.
Structure Level Pattern Image Note
TS22: renal tubule Present Regionally restricted S1A E14.5 GR , S1A E14.5 Merge Expression in proximal tubules.
Specimen S1A E16.5 GR: embryonic day 16.5 (more )
Note: Double labeled: red - Nr3c1; green - LTL.
Structure Level Pattern Image Note
TS24: renal tubule Present Regionally restricted S1A E16.5 GR , S1A E16.5 Merge Expression in proximal tubules.
Specimen S1A E18.5 GR: embryonic day 18.5 (more )
Note: Double labeled: red - Nr3c1; green - LTL.
Structure Level Pattern Image Note
TS26: renal proximal tubule Present S1A E18.5 Merge , S1A E18.5 GR
Specimen S1B E14.5 GR: embryonic day 14.5 (more )
Note: Double labeled: red - Nr3c1; green - DBA.
Structure Level Pattern Image Note
TS22: collecting duct Present S1B E14.5 GR , S1B E14.5 Merge
Specimen S1B E16.5 GR: embryonic day 16.5 (more )
Note: Double labeled: red - Nr3c1; green - DBA.
Structure Level Pattern Image Note
TS24: collecting duct Present S1B E16.5 GR , S1B E16.6 Merge
Specimen S1B E18.5 GR: embryonic day 18.5 (more )
Note: Double labeled: red - Nr3c1; green - DBA.
Structure Level Pattern Image Note
TS26: collecting duct Present S1B E18.5 GR , S1B E18.5 Merge
Specimen S2A E14.5 GR: embryonic day 14.5 (more )
Note: Double labeled: red - Nr3c1; green - Nphs1 (assay MGI:8262658).
Structure Cell Type Level Pattern Image Note
TS22: maturing glomerular tuft metanephric podocyte Present S2A E14.5 GR , S2A E14.5 Merge
Specimen S2A E16.5 GR: embryonic day 16.5 (more )
Note: Double labeled: red - Nr3c1; green - Nphs1 (assay MGI:8262658).
Structure Cell Type Level Pattern Image Note
TS24: maturing glomerular tuft metanephric podocyte Present S2A E16.5 GR , S2A E16.5 Merge
Specimen S2A E18.5 GR: embryonic day 18.5 (more )
Note: Double labeled: red - Nr3c1; green - Nphs1 (assay MGI:8262658).
Structure Cell Type Level Pattern Image Note
TS26: glomerular tuft metanephric podocyte Present S2A E18.5 Merge , S2A E18.5 GR
Specimen S2B E14.5 GR: embryonic day 14.5 (more )
Note: Double labeled: red - Nr3c1; green - Meis1 (assay MGI:8262657) and Meis2 (assay MGI:8262668) and Meis3 (assay MGI:8262669).
Structure Level Pattern Image Note
TS22: renal interstitium Present S2B E14.5 GR , S2B E14.5 Merge Expression in stroma.
Specimen S2B E16.5 GR: embryonic day 16.5 (more )
Note: Double labeled: red - Nr3c1; green - Meis1 (assay MGI:8262657) and Meis2 (assay MGI:8262668) and Meis3 (assay MGI:8262669).
Structure Level Pattern Image Note
TS24: renal interstitium Present S2B E16.5 Merge , S2B E16.5 GR Expression in stroma.
Specimen S2B E18.5 GR: embryonic day 18.5 (more )
Note: Double labeled: red - Nr3c1; green - Meis1 (assay MGI:8262657) and Meis2 (assay MGI:8262668) and Meis3 (assay MGI:8262669).
Structure Level Pattern Image Note
TS26: renal interstitium Present S2B E18.5 GR , S2B E18.5 Merge Expression in stroma.
Specimen EV2A Control GR: embryonic day 18.5 (more )
Note: Triple labeled: red - Nr3c1; green - DBA; yellow - LTL.
Structure Level Pattern Image Note
TS26: metanephros Present EV2A Control Inset , EV2A Control GR , EV2A Control merge
Specimen EV2A GF-null GR: embryonic day 18.5; Nr3c1tm1Gsc/Nr3c1tm1Gsc (more )
Note: Triple labeled: red - Nr3c1; green - DBA; yellow - LTL.
Structure Level Pattern Image Note
TS26: metanephros Absent EV2A GR-null merged , EV2A GR-null Inset , EV2A GR-null GR Loss of expression confirmed.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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10/06/2026
MGI 6.29 		The Jackson Laboratory