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Gene Expression Data
Assay Details
Assay
Reference: J:372845 Napoli FR, et al., Microphthalmia and Disrupted Retinal Development Due to a LacZ Knock-in/Knock-Out Allele at the Vsx2 Locus. Eye Brain. 2024;16:115-131
Assay type: Immunohistochemistry
MGI Accession ID: MGI:8257012
Gene symbol: Vsx2
Gene name: visual system homeobox 2
Results
Specimen 1D: embryonic day 15.5; Vsx2tm1b(EUCOMM)Wtsi/Vsx2+ (more )
Structure Level Pattern Image Note
TS23: retina Present 1D left , 1D right
Specimen 1E: embryonic day 15.5; Vsx2tm1b(EUCOMM)Wtsi/Vsx2tm1b(EUCOMM)Wtsi (more )
Structure Level Pattern Image Note
TS23: retina Present Regionally restricted 1E right , 1E left Continued differentially localized expression. Mutant protein lacked nuclear localization.
Specimen 1F/H/J: postnatal day 28; Vsx2tm1b(EUCOMM)Wtsi/Vsx2+ (more )
Note: Double labeled: red - Vsx2 protein; green - Vsx2 reporter (assay MGI:8257011).
Structure Level Pattern Image Note
TS28: retina inner nuclear layer Present 1F , 1H , 1I Expression co-localized with Vsx2 reporter.
Specimen 2A: embryonic day 10.5; Vsx2tm1b(EUCOMM)Wtsi/Vsx2+ (more )
Structure Level Pattern Image Note
TS17: retina Present 2A
Specimen 2G: embryonic day 10.5; Vsx2tm1b(EUCOMM)Wtsi/Vsx2tm1b(EUCOMM)Wtsi (more )
Structure Level Pattern Image Note
TS17: retina Present 2G Expression similar to that of control.
Specimen 2M: embryonic day 11.5; Vsx2tm1b(EUCOMM)Wtsi/Vsx2+ (more )
Structure Level Pattern Image Note
TS19: retina Present 2M
Specimen 2S: embryonic day 11.5; Vsx2tm1b(EUCOMM)Wtsi/Vsx2tm1b(EUCOMM)Wtsi (more )
Structure Level Pattern Image Note
TS19: retina Present 2S Expression unaltered compared to control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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10/06/2026
MGI 6.29 		The Jackson Laboratory