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Gene Expression Data
Assay Details
Assay
Reference: J:298302 Ru J, et al., Malformation of Tear Ducts Underlies the Epiphora and Precocious Eyelid Opening in Prickle 1 Mutant Mice: Genetic Implications for Tear Duct Genesis. Invest Ophthalmol Vis Sci. 2020 Nov 2;61(13):6
Assay type: RNA in situ
MGI Accession ID: MGI:8192516
Gene symbol: Wnt6
Gene name: WNT family member 6
Probe: Wnt6 probe
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 5E/F: embryonic day 11.0 (more )
Note: Double labeled: purple - Wnt6; red - Trp63 (assay MGI:8192497).
Structure Level Pattern Image Note
TS18: eye surface ectoderm Strong 5E , 5F Highly expressed in tear duct and skin epithelium.
TS18: naso-lacrimal groove Strong 5E , 5F Highly expressed in tear duct and skin epithelium.
Specimen S3M: embryonic day 11.0 (more )
Note: Double labeled: purple - Wnt6; red - Trp63 (assay MGI:8192497).
Structure Level Pattern Image Note
TS18: naso-lacrimal groove Strong S3M p63 , S3M Highly expressed in tear duct.
Specimen 6G/H WT: embryonic day 11.0 (more )
Note: Double labeled: purple - Wnt6; red - Trp63 (assay MGI:8192497).
Structure Level Pattern Image Note
TS18: naso-lacrimal groove Present 6H WT , 6G WT
Specimen 6G/H b/b: embryonic day 11.0; Prickle1tm1.2Asw/Prickle1tm1.2Asw (more )
Note: Double labeled: purple - Wnt6; red - Trp63 (assay MGI:8192497).
Structure Level Pattern Image Note
TS18: naso-lacrimal groove Present 6H b/b , 6G b/b Expression similar to wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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09/15/2026
MGI 6.29 		The Jackson Laboratory