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Gene Expression Data
Assay Details
Assay
Reference: J:182740 Moya IM, et al., Stalk cell phenotype depends on integration of Notch and Smad1/5 signaling cascades. Dev Cell. 2012 Mar 13;22(3):501-14
Assay type: Immunohistochemistry
MGI Accession ID: MGI:8187634
Gene symbol: Des
Gene name: desmin
Antibody: Anti-Desmin (ab8592)
Detection system: Secondary antibody coupled to Alexa Fluor 568
Results
Specimen S2D Ctrl left: embryonic day 9.5; Smad1tm2Rob/Smad1+, Smad5tm1Huy/Smad5+ (more )
Note: Double labeled: red - Des; green - Pecam1 (assay MGI:8187623).
Structure Cell Type Level Pattern Image Note
TS15: yolk sac blood vessel pericyte Present S2D Ctrl YS Desmin , S2D Ctrl YS merge

Specimen S2D dKO left: embryonic day 9.5; Smad1tm2Rob/Smad1tm2Rob, Smad5tm1Huy/Smad5tm1Huy, Tg(Tek-cre)1Ywa/0 (more )
Note: Conditional mutant. Double labeled: red - Des; green - Pecam1 (assay MGI:8187623).
Structure Cell Type Level Pattern Image Note
TS15: yolk sac blood vessel pericyte Present S2D dKO YS Desmin , S2D dKO YS merge Similar as in the control.

Specimen S2D Ctrl right: embryonic day 9.5; Smad1tm2Rob/Smad1+, Smad5tm1Huy/Smad5+ (more )
Note: Double labeled: red - Des; green - Pecam1 (assay MGI:8187623).
Structure Cell Type Level Pattern Image Note
TS15: dorsal aorta pericyte Present S2D Ctrl Aorta merge , S2D Ctrl Aorta Desmin

Specimen S2D dKO right: embryonic day 9.5; Smad1tm2Rob/Smad1tm2Rob, Smad5tm1Huy/Smad5tm1Huy, Tg(Tek-cre)1Ywa/0 (more )
Note: Conditional mutant. Double labeled: red - Des; green - Pecam1 (assay MGI:8187623).
Structure Cell Type Level Pattern Image Note
TS15: dorsal aorta pericyte Present S2D dKO Aorta merge , S2D dKO Aorta Desmin Similar as in the control.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory