Arx Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:178173 Mastracci TL, et al., Nkx2.2 and Arx genetically interact to regulate pancreatic endocrine cell development and endocrine hormone expression. Dev Biol. 2011 Nov 1;359(1):1-11
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:8161243
Gene symbol:	Arx
Gene name:	aristaless related homeobox

Antibody:	anti-Arx
Detection system:	Secondary antibody coupled to Cy2

Results

1K ©

Specimen 1K: embryonic day 10.5; Nkx2-2^tm3Suss/Nkx2-2⁺ (more

)
Note: Double labeled: green - Arx; red - Gcg (assay MGI:8161242).

Structure	Cell Type	Level	Pattern	Image	Note
TS17: pancreas primordium	pancreatic A cell	Present		1K	A subset of positive cells coexpressed with Gcg in the alpha cells.

1M ©

Specimen 1M: embryonic day 10.5; Nkx2-2^tm3Suss/Nkx2-2^tm3Suss (more

)
Note: Double labeled: green - Arx; red - Gcg (assay MGI:8161242).

Structure	Cell Type	Level	Pattern	Image	Note
TS17: pancreas primordium	pancreatic A cell	Present		1M	Expressed in the remaining Gcg-positive cells in the mutant.

2I ©

Specimen 2I: embryonic day 12.5 (more

)
Note: Double labeled: green - Arx; red - Neurog3 (assay MGI:8161633).

Structure	Level	Pattern	Image	Note
TS20: pancreas	Present		2I	A small population of Neurog3+ cells also coexpressed Arx. These cells were located in or adjacent to the epithelial cords (Sox9+ in the adjacent section 2J).

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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