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Gene Expression Data
Assay Details
Assay
Reference: J:297650 Roeseler DA, et al., Gbx2 is required for the migration and survival of a subpopulation of trigeminal cranial neural crest cells. J Dev Biol. 2020;8(33)
Assay type: RNA in situ
MGI Accession ID: MGI:7840235
Gene symbol: Tbx20
Gene name: T-box 20
Probe: Tbx20 probe
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 2C: embryonic day 9.5 (more )
Note: Genetic background of specimen was either wild type or heterozygous.
Structure Cell Type Level Pattern Image Note
TS15: rhombomere 2 motor neuron Present Regionally restricted 2C Expression in motor neurons in ventral progenitor domains in rhombomeres 2-5 in wild type.
TS15: rhombomere 3 motor neuron Present Regionally restricted 2C Expression in motor neurons in ventral progenitor domains in rhombomeres 2-5 in wild type.
TS15: rhombomere 4 motor neuron Present Regionally restricted 2C Expression in motor neurons in ventral progenitor domains in rhombomeres 2-5 in wild type.
TS15: rhombomere 5 motor neuron Present Regionally restricted 2C Expression in motor neurons in ventral progenitor domains in rhombomeres 2-5 in wild type.

Specimen 2D: embryonic day 9.5; Gbx2tm1Mrt/Gbx2tm1Mrt (more )
Structure Cell Type Level Pattern Image Note
TS15: rhombomere 2 motor neuron Weak 2D Expression in rhombomere 2 motor neurons significantly reduced compared to wild type.
TS15: rhombomere 3 motor neuron Present Regionally restricted 2D Expression in motor neurons in ventral progenitor domains.
TS15: rhombomere 4 motor neuron Present Regionally restricted 2D Expression in motor neurons in ventral progenitor domains.
TS15: rhombomere 5 motor neuron Present Regionally restricted 2D Expression in motor neurons in ventral progenitor domains.

Specimen 2E: embryonic day 10.5 (more )
Note: Genetic background of specimen was either wild type or heterozygous.
Structure Cell Type Level Pattern Image Note
TS17: rhombomere 2 motor neuron Present Regionally restricted 2E Expression in motor neurons in ventral progenitor domain and beginning to migrate dorsolaterally from rhombomere 2.
TS17: rhombomere 3 motor neuron Present Regionally restricted 2E Expression in motor neurons in ventral progenitor domains in wild type .
TS17: rhombomere 4 motor neuron Present Regionally restricted 2E Expression in motor neurons in ventral progenitor domains in wild type .
TS17: rhombomere 5 motor neuron Present Regionally restricted 2E Expression in motor neurons in ventral progenitor domains in wild type .

Specimen 2F: embryonic day 10.5; Gbx2tm1Mrt/Gbx2tm1Mrt (more )
Structure Cell Type Level Pattern Image Note
TS17: rhombomere 2 motor neuron Weak 2F Expression in rhombomere 2 motor neurons significantly reduced compared to wild type.
TS17: rhombomere 3 motor neuron Present Regionally restricted 2F Expression in motor neurons in ventral progenitor domains wild type.
TS17: rhombomere 4 motor neuron Present Regionally restricted 2F Expression in motor neurons in ventral progenitor domains wild type.
TS17: rhombomere 5 motor neuron Present Regionally restricted 2F Expression in motor neurons in ventral progenitor domains wild type.

Specimen 2G: embryonic day 9.5 (more )
Note: Genetic background of specimen was either wild type or heterozygous. Double labeled: blue - Tbx20; orange - Egr2 (assay MGI:7840234).
Structure Level Pattern Image Note
TS15: rhombomere 2 Present 2G
TS15: rhombomere 3 Present 2G
TS15: rhombomere 4 Present 2G
TS15: rhombomere 5 Present 2G

Specimen 2H: embryonic day 9.5; Gbx2tm1Mrt/Gbx2tm1Mrt (more )
Note: Double labeled: blue - Tbx20; orange - Egr2 (assay MGI:7840234).
Structure Level Pattern Image Note
TS15: rhombomere 2 Present 2H
TS15: rhombomere 3 Present 2H
TS15: rhombomere 4 Present 2H
TS15: rhombomere 5 Present 2H


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory