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Gene Expression Data
Assay Details
Assay
Reference: J:297650 Roeseler DA, et al., Gbx2 is required for the migration and survival of a subpopulation of trigeminal cranial neural crest cells. J Dev Biol. 2020;8(33)
Assay type: RNA in situ
MGI Accession ID: MGI:7840234
Gene symbol: Egr2
Gene name: early growth response 2
Probe: Krox20 probe
Probe preparation: Antisense labelled with fluorescein RNA
Results
Specimen 2G: embryonic day 9.5 (more )
Note: Genetic background of specimen was either wild type or heterozygous. Double labeled: orange - Egr2; blue - Tbx20 (assay MGI:7840235).
Structure Level Pattern Image Note
TS15: rhombomere 3 Weak 2G Expression downregulated in rhombomere 3 at E9.5 in wild type.
TS15: rhombomere 2 Present 2G
TS15: rhombomere 4 Present 2G
TS15: rhombomere 5 Present 2G
Specimen 2H: embryonic day 9.5; Gbx2tm1Mrt/Gbx2tm1Mrt (more )
Note: Double labeled: orange - Egr2; blue - Tbx20 (assay MGI:7840235).
Structure Level Pattern Image Note
TS15: rhombomere 3 Present 2H Persistent ectopic expression in dorsal neural tube of rhombomere 3.
TS15: rhombomere 2 Present 2H
TS15: rhombomere 4 Present 2H
TS15: rhombomere 5 Present 2H
Specimen 3E: embryonic day 9.5 (more )
Note: Genetic background of specimen was either wild type or heterozygous. Double labeled: orange - Egr2; blue - Sox10 (assay MGI:7840239).
Structure Level Pattern Image Note
TS15: rhombomere 3 Weak 3E Expression downregulated in rhombomere 3 at E9.5 in wild type.
Specimen 3F: embryonic day 9.5; Gbx2tm1Mrt/Gbx2tm1Mrt (more )
Note: Double labeled: orange - Egr2; blue - Sox10 (assay MGI:7840239).
Structure Level Pattern Image Note
TS15: rhombomere 3 Present Regionally restricted 3F Expression perisists in rhombomere 3. No colocalization with Sox2 expression at boundary of rhombomere 2 and 3.
Specimen 3G: embryonic day 9.5 (more )
Note: Genetic background of specimen was either wild type or heterozygous. Double labeled: orange - Egr2; blue - Sox10 (assay MGI:7840239).
Structure Level Pattern Image Note
TS15: rhombomere 3 Weak 3G Expression downregulated in rhombomere 3 at E9.5 in wild type.
Specimen 3H: embryonic day 9.5; Gbx2tm1Mrt/Gbx2tm1Mrt (more )
Note: Double labeled: orange - Egr2; blue - Sox10 (assay MGI:7840239).
Structure Level Pattern Image Note
TS15: rhombomere 3 Present Regionally restricted 3H Expression perisists in rhombomere 3. No colocalization with Sox2 expression at boundary of rhombomere 2 and 3.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory