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Gene Expression Data
Assay Details
Assay
Reference: J:316648 Suflita MT, et al., Ground-state transcriptional requirements for skin-derived precursors. Stem Cells Dev. 2013 Jun 15;22(12):1779-88
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7785117
Gene symbol: Foxd3
Gene name: forkhead box D3
Antibody: Anti-Foxd3
Assay notes: Then antibody reference described two Foxd3 antibodies MGI:7785103 and MGI:7785096; the one used in this assay was not specified.
Results
Specimen 1C: embryonic day 8.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Tg(Wnt1-cre/Esr1*)10Rth/0 (more )
Note: Conditional mutant. Double labeled: magenta - Foxd3; green - Rosa-YFP.
Structure Cell Type Level Pattern Image Note
TS13: neural crest neural crest cell Present Regionally restricted 1C Expression was detected in premigratory and migratory cranial neural crest cells.
TS13: migrating neural crest migratory neural crest cell Present Regionally restricted 1C Expression was detected in migratory cranial neural crest cells.

Specimen 1F: embryonic day 12.5 (more )
Note: Double labeled: green - Foxd3; magenta - Sox2 (assay MGI:7785107).
Structure Level Pattern Image Note
TS20: dorsal root ganglion Present 1F At 12.5 dpc Foxd3 and Sox2 are co-expressed in the dorsal root ganglion.

Specimen 2A: embryonic day 12.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Tg(Wnt1-cre/Esr1*)10Rth/0 (more )
Note: Conditional mutant. Triple labeled: blue - Foxd3; red - Sox2 (assay MGI:7785107); green - Rosa-YFP.
Structure Level Pattern Image Note
TS21: vibrissa dermal component Present Regionally restricted 2A , 2B , 2D Expression was detected on the periphery of the dermal condensates. Co-expression with Sox2 was observed.

Specimen 2E: embryonic day 17.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Tg(Wnt1-cre/Esr1*)10Rth/0 (more )
Note: Conditional mutant. Triple labeled: blue - Foxd3; red - Sox2 (assay MGI:7785107); green - Rosa-YFP.
Structure Level Pattern Image Note
TS25: vibrissa dermal papilla Present 2F , 2E , 2H Expression was detected in the neural crest lineage in the dermal papilla. Co-expression with Sox2 was observed.
TS25: head mesenchyme Present Regionally restricted 2H , 2F , 2E Expression was observed in cranial mesenchyme that did not co-express with Sox2.

Specimen 5A: embryonic day 17.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Tg(Wnt1-cre/Esr1*)10Rth/0 (more )
Note: Conditional mutant. Triple labeled: blue - Foxd3; red - Sox2 (assay MGI:7785107); green - Rosa-YFP.
Structure Level Pattern Image Note
TS25: vibrissa follicle Present Regionally restricted 5B , 5A , 5D Expression was detected in the neural crest lineage, where it overlapped with Sox2.

Specimen 5E: embryonic day 17.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Sox2tm2Lpev/Sox2tm2Lpev, Tg(Wnt1-cre/Esr1*)10Rth/0 (more )
Note: Conditional mutant. Triple labeled: blue - Foxd3; red - Sox2 (assay MGI:7785107); green - Rosa-YFP.
Structure Level Pattern Image Note
TS25: vibrissa follicle Present Regionally restricted 5E , 5H , 5F Expression was detected in the neural crest lineage, but co-expression with Sox2 was lost in the mutant.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/30/2025
MGI 6.24
The Jackson Laboratory