About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:350071 Aaron KA, et al., Selection of viral capsids and promoters affects the efficacy of rescue of Tmprss3-deficient cochlea. Mol Ther Methods Clin Dev. 2023 Sep 14;30:413-428
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7717781
Gene symbol: Tubb3
Gene name: tubulin, beta 3 class III
Antibody: anti-Tuj1
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 1O: postnatal day 21 (more )
Note: Double labeled: red - Tubb3; blue - Sox2 (assay MGI:7717780).
Structure Cell Type Level Pattern Image Note
TS28: cochlea spiral ganglion neuron Present 1O
Specimen 1P: postnatal day 21; Tmprss3tm1Lex/Tmprss3+ (more )
Note: Double labeled: red - Tubb3; blue - Sox2 (assay MGI:7717780).
Structure Cell Type Level Pattern Image Note
TS28: cochlea spiral ganglion neuron Present 1P Similar as in the wild-type.
Specimen 1Q: postnatal day 21; Tmprss3tm1Lex/Tmprss3tm1Lex (more )
Note: Double labeled: red - Tubb3; blue - Sox2 (assay MGI:7717780).
Structure Cell Type Level Pattern Image Note
TS28: cochlea spiral ganglion neuron Present 1Q Similar as in the wild-type.
Specimen 1R: postnatal day 120 (more )
Note: Double labeled: red - Tubb3; blue - Sox2 (assay MGI:7717780).
Structure Cell Type Level Pattern Image Note
TS28: cochlea spiral ganglion neuron Present 1R
Specimen 1S: postnatal day 120; Tmprss3tm1Lex/Tmprss3+ (more )
Note: Double labeled: red - Tubb3; blue - Sox2 (assay MGI:7717780).
Structure Cell Type Level Pattern Image Note
TS28: cochlea spiral ganglion neuron Present 1S Similar as in the wild-type.
Specimen 1T: postnatal day 120; Tmprss3tm1Lex/Tmprss3tm1Lex (more )
Note: Double labeled: red - Tubb3; blue - Sox2 (assay MGI:7717780).
Structure Cell Type Level Pattern Image Note
TS28: cochlea spiral ganglion neuron Present 1T A significant loss was seen compared with the wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory