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Gene Expression Data
Assay Details
Assay
Reference: J:344830 Tsutsumi-Arai C, et al., A PTHrP Gradient Drives Mandibular Condylar Chondrogenesis via Runx2. J Dent Res. 2024 Jan;103(1):91-100
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7645408
Gene symbol: Runx2
Gene name: runt related transcription factor 2
Antibody: anti-RUNX2 (NBP1-89104)
Detection system: Secondary antibody coupled to Alexa Fluor 647
Results
Specimen 1D: postnatal day 3; Pthlhem1Nono/Pthlh+ (more )
Note: Multi-labeled: blue - Runx2; green - Col10a1 (assay MGI:7645407); red - Pthlh reporter (assay MGI:7645376); magenta - Sox9 (assay MGI:7645405).
Structure Level Pattern Image Note
TS27: mandible condylar process Present Regionally restricted 1d2 , 1d1 , 1D Expression is in the polymorphic layer, the flattened chondrocyte layer, and the upper hypertrophic layer.
Specimen 1E: postnatal day 3; Pthlhem1Nono/Pthlh+ (more )
Note: Double labeled: blue - Runx2; red - Pthlh reporter (assay MGI:7645376).
Structure Level Pattern Image Note
TS27: mandible condylar process Present Regionally restricted 1E Expression is in the polymorphic layer, the flattened chondrocyte layer, and the upper hypertrophic layer.
Specimen 3C Control E15.5: embryonic day 15.5; Pthlhem1Nono/Pthlh+ (more )
Structure Level Pattern Image Note
TS23: mandible condylar process Present Regionally restricted 3C E15.5 Control Expression is in the polymorphic layer.
Specimen 3C KO E15.5: embryonic day 15.5; Pthlhem1Nono/Pthlhem1Nono (more )
Structure Level Pattern Image Note
TS23: mandible condylar process Present Regionally restricted 3C E15.5 KO Expression is in the polymorphic layer.
Specimen 3C Control E18.5: embryonic day 18.5; Pthlhem1Nono/Pthlh+ (more )
Structure Level Pattern Image Note
TS26: mandible condylar process Present Regionally restricted 3C E18.5 Control Expression is in the polymorphic layer.
Specimen 3C KO E18.5: embryonic day 18.5; Pthlhem1Nono/Pthlhem1Nono (more )
Structure Level Pattern Image Note
TS26: mandible condylar process Present Regionally restricted 3C E18.5 KO Expression is in the polymorphic layer.
Specimen S1F: postnatal day 3; Pthlhem1Nono/Pthlh+ (more )
Note: Triple labeled: orange - Runx2; green - Pth1r (assay MGI:7645422); red - Pthlh reporter (assay MGI:7645376).
Structure Level Pattern Image Note
TS27: mandible condylar process Present Regionally restricted S1F Expression is in the polymorphic and flattened chondrocyte layers.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory