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Gene Expression Data
Assay Details
Assay
Reference: J:344830 Tsutsumi-Arai C, et al., A PTHrP Gradient Drives Mandibular Condylar Chondrogenesis via Runx2. J Dent Res. 2024 Jan;103(1):91-100
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7645386
Gene symbol: Sox9
Gene name: SRY (sex determining region Y)-box 9
Antibody: anti-Sox9 (AF3075)
Detection system: Secondary antibody coupled to Alexa Fluor 647
Results
Specimen 1C: postnatal day 3; Pthlhem1Nono/Pthlh+ (more )
Note: Double labeled: yellow - Sox9; red - Pthlh reporter (assay MGI:7645376).
Structure Cell Type Level Pattern Image Note
TS27: mandible condylar process chondrocyte Present Regionally restricted 1C Expression is in the chondrocyte layers.
Specimen 3D Control E15.5: embryonic day 15.5; Pthlhem1Nono/Pthlh+ (more )
Note: Double labeled: magenta - Sox9; red - Pthlh reporter (assay MGI:7645376).
Structure Level Pattern Image Note
TS23: mandible condylar process Present Regionally restricted 3D E15.5 Control Expression is in the chondrocyte layers.
Specimen 3D KO E15.5: embryonic day 15.5; Pthlhem1Nono/Pthlhem1Nono (more )
Note: Double labeled: magenta - Sox9; red - Pthlh reporter (assay MGI:7645376).
Structure Level Pattern Image Note
TS23: mandible condylar process Present Regionally restricted 3D E15.5 KO Expression in this mutant is the same as in controls.
Specimen 3D Control E18.5: embryonic day 18.5; Pthlhem1Nono/Pthlh+ (more )
Note: Double labeled: magenta - Sox9; red - Pthlh reporter (assay MGI:7645376).
Structure Level Pattern Image Note
TS26: mandible condylar process Present Regionally restricted 3D E18.5 Control Expression is in the chondrocyte layers.
Specimen 3D KO E18.5: embryonic day 18.5; Pthlhem1Nono/Pthlhem1Nono (more )
Note: Double labeled: magenta - Sox9; red - Pthlh reporter (assay MGI:7645376).
Structure Level Pattern Image Note
TS26: mandible condylar process Present Regionally restricted 3D E18.5 KO The expression domain was significantly reduced in this mutant compared to controls.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory