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Gene Expression Data
Assay Details
Assay
Reference: J:344830 Tsutsumi-Arai C, et al., A PTHrP Gradient Drives Mandibular Condylar Chondrogenesis via Runx2. J Dent Res. 2024 Jan;103(1):91-100
Assay type: RNA in situ
MGI Accession ID: MGI:7645309
Gene symbol: Runx2
Gene name: runt related transcription factor 2
Probe: Mm-Runx2 (414021)
Probe preparation: Antisense DNA
Visualized with: Chromogenic
Assay notes: RNAscope assay (Opal520).
Results
Specimen 5A1 Control: embryonic day 15.5; Pthlhem1Nono/Pthlh+ (more )
Note: Double labeled: green - Runx2; red - Pthlh reporter (assay MGI:7645376).
Structure Level Pattern Image Note
TS23: mandible condylar process Present Regionally restricted 5Aa1 Control E15.5 Expression is in the polymorphic layer.
Specimen 5A1 KO: embryonic day 15.5; Pthlhem1Nono/Pthlhem1Nono (more )
Note: Double labeled: green - Runx2; red - Pthlh reporter (assay MGI:7645376).
Structure Level Pattern Image Note
TS23: mandible condylar process Present Regionally restricted 5Aa1 KO E15.5 The expression domain is reduced in this mutant compared to controls.
Specimen 5A1 Control: embryonic day 18.5; Pthlhem1Nono/Pthlh+ (more )
Note: Double labeled: green - Runx2; red - Pthlh reporter (assay MGI:7645376).
Structure Level Pattern Image Note
TS26: mandible condylar process Present Regionally restricted 5Aa1 Control E18.5 Expression is in the polymorphic layer.
Specimen 5A1 KO: embryonic day 18.5; Pthlhem1Nono/Pthlhem1Nono (more )
Note: Double labeled: green - Runx2; red - Pthlh reporter (assay MGI:7645376).
Structure Level Pattern Image Note
TS26: mandible condylar process Present Regionally restricted 5Aa1 KO E18.5 The expression domain is reduced in this mutant compared to controls.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory