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Gene Expression Data
Assay Details
Assay
Reference: J:339076 Meng H, et al., Evidence for developmental vascular-associated necroptosis and its contribution to venous-lymphatic endothelial differentiation. Front Cell Dev Biol. 2023;11:1229788
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7643480
Gene symbol: Pecam1
Gene name: platelet/endothelial cell adhesion molecule 1
Antibody: MEC 13.3
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 1E left: embryonic day 10.5 (more )
Note: Double labeled: green - Pecam1; magenta - Mlkl (assay MGI:7643479).
Structure Cell Type Level Pattern Image Note
TS17: brain blood vessel blood vessel endothelial cell Present 1E left
Specimen 1G left: postnatal day 1 (more )
Note: Double labeled: green - Pecam1; magenta - Mlkl (assay MGI:7643479).
Structure Cell Type Level Pattern Image Note
TS27: skin blood vessel blood vessel endothelial cell Present 1G left
Specimen 2A WT: postnatal day 7 (more )
Note: Double labeled: green - Pecam1; magenta - Pdgfrb (assay MGI:7643482).
Structure Cell Type Level Pattern Image Note
TS28: brain blood vessel blood vessel endothelial cell Present 2A WT
Specimen 2A KO: postnatal day 7; Mlklem1Jhan/Mlklem1Jhan (more )
Note: Double labeled: green - Pecam1; magenta - Pdgfrb (assay MGI:7643482).
Structure Cell Type Level Pattern Image Note
TS28: brain blood vessel blood vessel endothelial cell Present 2A KO Similar as in the wild-type.
Specimen 2D WT: postnatal day 7 (more )
Note: Double labeled: green - Pecam1; magenta - Pdgfrb (assay MGI:7643482).
Structure Cell Type Level Pattern Image Note
TS28: skin blood vessel blood vessel endothelial cell Present 2D WT
Specimen 2D KO: postnatal day 7; Mlklem1Jhan/Mlklem1Jhan (more )
Note: Double labeled: green - Pecam1; magenta - Pdgfrb (assay MGI:7643482).
Structure Cell Type Level Pattern Image Note
TS28: skin blood vessel blood vessel endothelial cell Present 2D KO Similar as in the wild-type.
Specimen 3A WT: postnatal day 7 (more )
Note: Double labeled: green - Pecam1; magenta - Nr2f2 (assay MGI:7643485).
Structure Cell Type Level Pattern Image Note
TS28: brain blood vessel blood vessel endothelial cell Present 3A WT
Specimen 3A KO: postnatal day 7; Mlklem1Jhan/Mlklem1Jhan (more )
Note: Double labeled: green - Pecam1; magenta - Nr2f2 (assay MGI:7643485).
Structure Cell Type Level Pattern Image Note
TS28: brain blood vessel blood vessel endothelial cell Present 3A KO Similar as in the wild-type.
Specimen 3C WT: postnatal day 7 (more )
Note: Double labeled: green - Pecam1; magenta - Sox18 (assay MGI:7643483).
Structure Cell Type Level Pattern Image Note
TS28: brain blood vessel blood vessel endothelial cell Present 3C WT
Specimen 3C KO: postnatal day 7; Mlklem1Jhan/Mlklem1Jhan (more )
Note: Double labeled: green - Pecam1; magenta - Sox18 (assay MGI:7643483).
Structure Cell Type Level Pattern Image Note
TS28: brain blood vessel blood vessel endothelial cell Present 3C KO Similar as in the wild-type.
Specimen 3E WT: postnatal day 7 (more )
Note: Double labeled: green - Pecam1; magenta - Prox1 (assay MGI:7643484).
Structure Cell Type Level Pattern Image Note
TS28: brain blood vessel blood vessel endothelial cell Present 3E WT
Specimen 3E KO: postnatal day 7; Mlklem1Jhan/Mlklem1Jhan (more )
Note: Double labeled: green - Pecam1; magenta - Prox1 (assay MGI:7643484).
Structure Cell Type Level Pattern Image Note
TS28: brain blood vessel blood vessel endothelial cell Present 3E KO Similar as in the wild-type.
Specimen 4A WT: postnatal day 7 (more )
Note: Double labeled: green - Pecam1; magenta - Nr2f2 (assay MGI:7643485).
Structure Cell Type Level Pattern Image Note
TS28: skin blood vessel blood vessel endothelial cell Present 4A WT
Specimen 4A KO: postnatal day 7; Mlklem1Jhan/Mlklem1Jhan (more )
Note: Double labeled: green - Pecam1; magenta - Nr2f2 (assay MGI:7643485).
Structure Cell Type Level Pattern Image Note
TS28: skin blood vessel blood vessel endothelial cell Present 4A KO Similar as in the wild-type.
Specimen 4C WT: postnatal day 7 (more )
Note: Double labeled: green - Pecam1; magenta - Sox18 (assay MGI:7643483).
Structure Cell Type Level Pattern Image Note
TS28: skin blood vessel blood vessel endothelial cell Present 4C WT
Specimen 4C KO: postnatal day 7; Mlklem1Jhan/Mlklem1Jhan (more )
Note: Double labeled: green - Pecam1; magenta - Sox18 (assay MGI:7643483).
Structure Cell Type Level Pattern Image Note
TS28: skin blood vessel blood vessel endothelial cell Present 4C KO Similar as in the wild-type.
Specimen 4E WT: postnatal day 7 (more )
Note: Double labeled: green - Pecam1; magenta - Prox1 (assay MGI:7643484).
Structure Cell Type Level Pattern Image Note
TS28: skin blood vessel blood vessel endothelial cell Present 4E WT
Specimen 4E KO: postnatal day 7; Mlklem1Jhan/Mlklem1Jhan (more )
Note: Double labeled: green - Pecam1; magenta - Prox1 (assay MGI:7643484).
Structure Cell Type Level Pattern Image Note
TS28: skin blood vessel blood vessel endothelial cell Present 4E KO Similar as in the wild-type.
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory