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Gene Expression Data
Assay Details
Assay
Reference: J:347585 Leon NY, et al., Y chromosome damage underlies testicular abnormalities in ATR-X syndrome. iScience. 2024 May 17;27(5):109629
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7628672
Gene symbol: Zfpm2
Gene name: zinc finger protein, multitype 2
Antibody: anti-FOG2 (M-247) (sc-10755)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 1B Control: embryonic day 16.5; Atrxtm1Rjg/Y (more )
Note: Double labeled: green - Zfpm2; red - Gata4 (assay MGI:7628670).
Structure Cell Type Level Pattern Image Note
TS24: Sertoli cell Sertoli cell Present Regionally restricted 1B Control FOG2 , 1B Control (merged) Expression co-localized with Gata4 expression in both control and mutant Sertoli cells.
Specimen 1B ScAttrxKO: embryonic day 16.5; Atrxtm1Rjg/Y, Plekha5Tg(AMH-cre)1Flor/0 (more )
Note: Conditional mutant. Double labeled: green - Zfpm2; red - Gata4 (assay MGI:7628670).
Structure Cell Type Level Pattern Image Note
TS24: Sertoli cell Sertoli cell Present Regionally restricted 1B ScAtrxKO FOG2 , 1B ScAtrxKO (merged) Expression co-localized with Gata4 expression in both control and mutant Sertoli cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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