About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:249375 Smiley S, et al., Establishment of a cone photoreceptor transplantation platform based on a novel cone-GFP reporter mouse line. Sci Rep. 2016 Mar 11;6:22867
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7624345
Gene symbol: Opn1mw
Gene name: opsin 1 (cone pigments), medium-wave-sensitive (color blindness, deutan)
Antibody: anti-red/green Opsin (#AB5405)
Detection system: Secondary antibody
Results
Specimen 2 dorsal WT: postnatal adult (more )
Structure Cell Type Level Pattern Image Note
TS28: photoreceptor layer outer segment M cone cell Present 2_3-1 , 2_3-2
Specimen 2 dorsal GFP/GFP: postnatal adult; Ccdc136Gt(373F8)Cmhd/Ccdc136Gt(373F8)Cmhd (more )
Note: Double labeled: red - Opn1mw; green - Ccdc136 reporter (assay MGI:7624337).
Structure Cell Type Level Pattern Image Note
TS28: photoreceptor layer outer segment M cone cell Present 2_3-5 , 2_3-3 Low to undetectable GFP in the dorsal retina.
Specimen 2 central WT: postnatal adult (more )
Structure Cell Type Level Pattern Image Note
TS28: photoreceptor layer outer segment M cone cell Present 2_4-2 , 2_4-1
Specimen 2 central GFP/GFP: postnatal adult; Ccdc136Gt(373F8)Cmhd/Ccdc136Gt(373F8)Cmhd (more )
Note: Double labeled: red - Opn1mw; green - Ccdc136 reporter (assay MGI:7624337).
Structure Cell Type Level Pattern Image Note
TS28: photoreceptor layer outer segment M cone cell Present 2_4-5 , 2_4-3 Expression overlapped with GFP-expressing cells in the central retina.
Specimen 2 ventral WT: postnatal adult (more )
Structure Cell Type Level Pattern Image Note
TS28: photoreceptor layer outer segment M cone cell Weak 2_5-2 , 2_5-1 Low to undetectable in M opsin+ cells in the dorsal retina.
Specimen 2 ventral GFP/GFP: postnatal adult; Ccdc136Gt(373F8)Cmhd/Ccdc136Gt(373F8)Cmhd (more )
Note: Double labeled: red - Opn1mw; green - Ccdc136 reporter (assay MGI:7624337).
Structure Cell Type Level Pattern Image Note
TS28: photoreceptor layer outer segment M cone cell Weak 2_5-3 , 2_5-5 Low to undetectable in M opsin+ cells in the dorsal retina.
Specimen S4a: postnatal adult; Ccdc136Gt(373F8)Cmhd/Ccdc136Gt(373F8)Cmhd, Nrltm1Asw/Nrltm1Asw (more )
Note: Double labeled: red - Opn1mw; green - Ccdc136 reporter (assay MGI:7624337).
Structure Cell Type Level Pattern Image Note
TS28: photoreceptor layer outer segment M cone cell Present S4a merge-3 , S4a M opsin A shortened outer segment was shown, similar as in Nrl-/-.
Specimen S4e +/+: postnatal adult (more )
Note: Double labeled: red - Opn1mw; green - Opn1sw (assay MGI:7624343).
Structure Cell Type Level Pattern Image Note
TS28: retina M cone cell Present S4e +/+
Specimen S4e GFP/GFP: postnatal adult; Ccdc136Gt(373F8)Cmhd/Ccdc136Gt(373F8)Cmhd (more )
Note: Double labeled: red - Opn1mw; green - Opn1sw (assay MGI:7624343).
Structure Cell Type Level Pattern Image Note
TS28: retina M cone cell Present S4e GFP/GFP Similar as in the wild-type.
Specimen S4e Nrl-/-: postnatal adult; Nrltm1Asw/Nrltm1Asw (more )
Note: Double labeled: red - Opn1mw; green - Opn1sw (assay MGI:7624343).
Structure Cell Type Level Pattern Image Note
TS28: retina M cone cell Present S4e -/- Lost regular expression pattern.
Specimen S4e Nrl-/-;GFP/+: postnatal adult; Ccdc136Gt(373F8)Cmhd/Ccdc136+, Nrltm1Asw/Nrltm1Asw (more )
Note: Double labeled: red - Opn1mw; green - Opn1sw (assay MGI:7624343).
Structure Cell Type Level Pattern Image Note
TS28: retina M cone cell Present S4e -/-;GFP/+ Lost regular expression pattern, similar as in the Nrl-/-.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory