About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:279927 Batiuk MY, et al., An immunoaffinity-based method for isolating ultrapure adult astrocytes based on ATP1B2 targeting by the ACSA-2 antibody. J Biol Chem. 2017 May 26;292(21):8874-8891
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7619797
Gene symbol: Aif1
Gene name: allograft inflammatory factor 1
Antibody: anti-Iba1 (234003)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 10B row 1/2: postnatal month 6; Apptm3.1Tcs/Apptm3.1Tcs (more )
Note: Double labeled: green - Aif1; magenta - Atp1b2 (assay MGI:7619762).
Structure Cell Type Level Pattern Image Note
TS28: cerebral cortex microglial cell Present Clusters 10B IBA1 (low mag row 1) , 10B IBA1 (high mag row 2) , 10B Merge (high mag row 2) Expression in the App<NL-G-F> cortex was detected in plaques surrounded by activated microglia. The aggregates of microglia exclude astrocytes, and do not co-localize staining for Atp1a2.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/21/2024
MGI 6.23 		The Jackson Laboratory