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Gene Expression Data
Assay Details
Assay
Reference: J:302618 Wang B, et al., The autophagy-inducing kinases, ULK1 and ULK2, regulate axon guidance in the developing mouse forebrain via a noncanonical pathway. Autophagy. 2018;14(5):796-811
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7616432
Gene symbol: Sox2
Gene name: SRY (sex determining region Y)-box 2
Antibody: Anti-Sox2 (Y-17; sc-17320)
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 4A Control: postnatal adult (more )
Note: Triple labeled: green - Sox2; red - Mki67 (assay MGI:7616434); blue - Rbfox3 (assay MGI:7616435).
Structure Cell Type Level Pattern Image Note
TS28: dentate gyrus subgranular zone neural stem cell Present 4A SOX2 control , 4A Merge control
Specimen 4A Ulk1/2-cDKO: postnatal adult; Tg(Nes-cre)1Kln/0, Ulk1tm1.1Thsn/Ulk1tm1.1Thsn, Ulk2tm1.1Thsn/Ulk2tm1Thsn (more )
Note: Conditional mutant. Triple labeled: green - Sox2; red - Mki67 (assay MGI:7616434); blue - Rbfox3 (assay MGI:7616435).
Structure Cell Type Level Pattern Image Note
TS28: dentate gyrus subgranular zone neural stem cell Present 4A Merge Ulk1/2cDKO , 4A SOX2 Ulk1/2cDKO Similar as in the control.
Specimen S4A Control: postnatal day 21; Rb1cc1tm1.1Guan/Rb1cc1tm1.1Guan (more )
Structure Cell Type Level Pattern Image Note
TS28: dentate gyrus subgranular zone neural stem cell Present S4A upper left
Specimen S4A Rb1cc1-cKO: postnatal day 21; Rb1cc1tm1.1Guan/Rb1cc1tm1.1Guan, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: dentate gyrus subgranular zone neural stem cell Present S4A upper right Significantly decreased expression compared with the control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory