Gene Expression Data
Assay Details
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Assay
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Reference:
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J:209053
Hoekstra EJ, et al., Lmx1a is an activator of Rgs4 and Grb10 and is responsible for the correct specification of rostral and medial mdDA neurons. Eur J Neurosci. 2013 Jan;37(1):23-32
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:7595756
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Gene symbol:
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Dstn
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Gene name:
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destrin
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Probe:
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Dstn cDNA
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Visualized with:
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Alkaline phosphatase
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Results
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Specimen
2F:
embryonic day 14.5
(more  )
Note: Double labeled: purple - Dstn; brown - Th (assay MGI:7595776).
Specimen
2F:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Note:
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Double labeled: purple - Dstn; brown - Th (assay MGI:7595776).
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: brain |
Present |
Widespread |
2F
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Expressed throughout the brain, and clearly overlapped with the mesodiencephalic dopamine neuronal field.
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Specimen
2K:
embryonic day 14.5
(more )
Note: Double labeled: purple - Dstn; brown - Th (assay MGI:7595776).
Specimen
2K:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Note:
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Double labeled: purple - Dstn; brown - Th (assay MGI:7595776).
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: brain |
Present |
Widespread |
2K
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Expressed in the entire brain, with an enrichment in the ventricular and intermediate zones, partially overlapping with the mesodiencephalic dopamine progenitor area.
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| TS22: midbrain ventricular layer |
Present |
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2K
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Specimen
2O:
embryonic day 14.5
(more )
Note: Double labeled: purple - Dstn; brown - Th (assay MGI:7595776).
Specimen
2O:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Note:
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Double labeled: purple - Dstn; brown - Th (assay MGI:7595776).
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: brain |
Present |
Widespread |
2O
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Expressed in the entire brain, with an enrichment in the ventricular and intermediate zones, partially overlapping with the mesodiencephalic dopamine progenitor area.
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| TS22: midbrain ventricular layer |
Present |
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2O
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Specimen
3E:
embryonic day 14.5
(more )
Note: Double labeled: purple - Dstn; brown - Th (assay MGI:7595776).
Specimen
3E:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Note:
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Double labeled: purple - Dstn; brown - Th (assay MGI:7595776).
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: brain |
Present |
Widespread |
3E
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Expressed in the entire brain, with an enrichment in the ventricular and intermediate zones, partially overlapping with the mesodiencephalic dopamine progenitor area.
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| TS22: midbrain ventricular layer |
Present |
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3E
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| TS22: brainstem nucleus |
Present |
Regionally restricted |
3E
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Expressed in the red nucleus area, adjacent to the mesodiencephalic dopamine neuronal field.
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Specimen
3N:
embryonic day 14.5
(more )
Note: Double labeled: purple - Dstn; brown - Th (assay MGI:7595776).
Specimen
3N:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Note:
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Double labeled: purple - Dstn; brown - Th (assay MGI:7595776).
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS22: brain |
Present |
Widespread |
3N
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Expressed in the entire brain, with an enrichment in the ventricular and intermediate zones, partially overlapping with the mesodiencephalic dopamine progenitor area.
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| TS22: midbrain ventricular layer |
Present |
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3N
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| TS22: brainstem nucleus |
Present |
Regionally restricted |
3N
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Expressed in the red nucleus area, adjacent to the mesodiencephalic dopamine neuronal field.
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Specimen
3W:
embryonic day 14.5
(more )
Note: Double labeled: purple - Dstn; brown - Th (assay MGI:7595776).
Specimen
3W:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Note:
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Double labeled: purple - Dstn; brown - Th (assay MGI:7595776).
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS22: brain |
Present |
Widespread |
3W
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Expressed in the entire brain, with an enrichment in the ventricular and intermediate zones, partially overlapping with the mesodiencephalic dopamine progenitor area.
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| TS22: midbrain ventricular layer |
Present |
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3W
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Specimen
5A:
embryonic day 14.5
(more )
Note: Double labeled: purple - Dstn; brown - Th (assay MGI:7595776).
Specimen
5A:
(close )
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Genetic Background:
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involves: C3HeB/Fe * C57BL/6J
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Note:
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Double labeled: purple - Dstn; brown - Th (assay MGI:7595776).
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS22: midbrain |
Present |
Widespread |
5A
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Specimen
5B:
embryonic day 14.5
(more )
Note: Double labeled: purple - Dstn; brown - Th (assay MGI:7595776).
Specimen
5B:
(close )
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Genetic Background:
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involves: C3HeB/Fe * C57BL/6J
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Note:
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Double labeled: purple - Dstn; brown - Th (assay MGI:7595776).
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: midbrain |
Present |
Widespread |
5B
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Specimen
5C/C':
embryonic day 14.5
(more )
Note: Double labeled: purple - Dstn; brown - Th (assay MGI:7595776).
Specimen
5C/C':
(close )
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Genetic Background:
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involves: C3HeB/Fe * C57BL/6J
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
|
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Note:
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Double labeled: purple - Dstn; brown - Th (assay MGI:7595776).
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: midbrain |
Present |
Widespread |
5C'
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5C
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Specimen
5D/D':
embryonic day 14.5
(more )
Note: Double labeled: purple - Dstn; brown - Th (assay MGI:7595776).
Specimen
5D/D':
(close )
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Genetic Background:
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involves: C3HeB/Fe * C57BL/6J
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
|
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Note:
|
Double labeled: purple - Dstn; brown - Th (assay MGI:7595776).
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS22: midbrain |
Present |
Widespread |
5D'
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5D
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Specimen
5E:
embryonic day 14.5
(more )
Note: Double labeled: purple - Dstn; brown - Th (assay MGI:7595776).
Specimen
5E:
(close )
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Genetic Background:
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involves: C3HeB/Fe * C57BL/6J
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
|
Cryosection
|
|
Note:
|
Double labeled: purple - Dstn; brown - Th (assay MGI:7595776).
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS22: midbrain |
Present |
Widespread |
5E
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Specimen
5F:
embryonic day 14.5; Lmx1adr/ Lmx1adr
(more )
Note: Double labeled: purple - Dstn; brown - Th (assay MGI:7595776).
Specimen
5F:
(close )
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Genetic Background:
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involves: C3HeB/Fe * C57BL/6J
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Mutant Allele(s):
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Lmx1adr/Lmx1adr
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
|
|
Note:
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Double labeled: purple - Dstn; brown - Th (assay MGI:7595776).
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS22: midbrain |
Present |
Widespread |
5F
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Similar as in the wild-type.
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Specimen
5G:
embryonic day 14.5; Lmx1adr/ Lmx1adr
(more )
Note: Double labeled: purple - Dstn; brown - Th (assay MGI:7595776).
Specimen
5G:
(close )
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Genetic Background:
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involves: C3HeB/Fe * C57BL/6J
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Mutant Allele(s):
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Lmx1adr/Lmx1adr
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
|
|
Note:
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Double labeled: purple - Dstn; brown - Th (assay MGI:7595776).
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS22: midbrain |
Present |
Widespread |
5G
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Similar as in the wild-type.
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Specimen
5H/H':
embryonic day 14.5; Lmx1adr/ Lmx1adr
(more )
Note: Double labeled: purple - Dstn; brown - Th (assay MGI:7595776).
Specimen
5H/H':
(close )
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Genetic Background:
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involves: C3HeB/Fe * C57BL/6J
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Mutant Allele(s):
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Lmx1adr/Lmx1adr
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
|
|
Note:
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Double labeled: purple - Dstn; brown - Th (assay MGI:7595776).
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS22: midbrain |
Present |
Widespread |
5H
,
5H'
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Similar as in the wild-type.
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Specimen
5I/I':
embryonic day 14.5; Lmx1adr/ Lmx1adr
(more )
Note: Double labeled: purple - Dstn; brown - Th (assay MGI:7595776).
Specimen
5I/I':
(close )
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Genetic Background:
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involves: C3HeB/Fe * C57BL/6J
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Mutant Allele(s):
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Lmx1adr/Lmx1adr
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
|
|
Note:
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Double labeled: purple - Dstn; brown - Th (assay MGI:7595776).
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS22: midbrain |
Present |
Widespread |
5I'
,
5I
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Similar as in the wild-type.
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Specimen
5J:
embryonic day 14.5; Lmx1adr/ Lmx1adr
(more )
Note: Double labeled: purple - Dstn; brown - Th (assay MGI:7595776).
Specimen
5J:
(close )
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Genetic Background:
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involves: C3HeB/Fe * C57BL/6J
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Mutant Allele(s):
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Lmx1adr/Lmx1adr
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Note:
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Double labeled: purple - Dstn; brown - Th (assay MGI:7595776).
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS22: midbrain |
Present |
Widespread |
5J
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Similar as in the wild-type.
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