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Gene Expression Data
Assay Details
Assay
Reference: J:190564 Tavares AL, et al., Ectodermal-derived Endothelin1 is required for patterning the distal and intermediate domains of the mouse mandibular arch. Dev Biol. 2012 Nov 1;371(1):47-56
Assay type: RNA in situ
MGI Accession ID: MGI:7580433
Gene symbol: Dlx5
Gene name: distal-less homeobox 5
Probe: Dlx5 probe
Probe preparation: Antisense labelled with fluorescein RNA
Visualized with: Alkaline phosphatase
Results
Specimen 7E: embryonic day 10.5; Edn1tm1Ywa/Edn1tm1Ywa (more )
Note: Double labeled: magenta - Dlx5; blue - Nkx3-2 (assay MGI:7580436).
Structure Level Pattern Image Note
TS17: 1st branchial arch Present 7E
Specimen 7F: embryonic day 10.5; Edn1tm1Ywa/Edn1tm1Ywa, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant. Double labeled: magenta - Dlx5; blue - Nkx3-2 (assay MGI:7580436).
Structure Level Pattern Image Note
TS17: 1st branchial arch mesenchyme Present Regionally restricted 7F Residual mesenchyme expression confined to domain in which Dlx5 is absent.
Specimen 8E: embryonic day 10.5; Edn1tm1Ywa/Edn1tm1Ywa (more )
Note: Double labeled: magenta - Dlx5; blue - Nkx3-2 (assay MGI:7580436).
Structure Level Pattern Image Note
TS17: 1st branchial arch mesenchyme Present Regionally restricted 8E Mesenchymal expression overlaps with that of Nkx3.2.
Specimen 8F: embryonic day 10.5; Edn1tm1Ywa/Edn1tm1Ywa, Tg(Tcfap2a-cre)1Will/0 (more )
Note: Conditional mutant. Double labeled: magenta - Dlx5; blue - Nkx3-2 (assay MGI:7580436).
Structure Level Pattern Image Note
TS17: 1st branchial arch mesenchyme Present Regionally restricted 8F Expression lost in same central arch domain as for Nkx3.2.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/09/2025
MGI 6.24 		The Jackson Laboratory