Th Immunohistochemistry Gene Expression Assay - GXD

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Gene Expression Data
Assay Details

Assay

Reference:	J:316482 Kouwenhoven WM, et al., Nkx2.9 Contributes to Mid-Hindbrain Patterning by Regulation of mdDA Neuronal Cell-Fate and Repression of a Hindbrain-Specific Cell-Fate. Int J Mol Sci. 2021 Nov 23;22(23)
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:7576023
Gene symbol:	Th
Gene name:	tyrosine hydroxylase

Antibody:	anti-TH
Detection system:	Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase

Results

2B-1 ©

Specimen 2B lateral to medial 1: embryonic day 12.5 (more

)
Note: Double labeled: brown - Th; blue - Nkx2-9 (assay MGI:7576004).

Structure	Cell Type	Level	Pattern	Image	Note
TS20: midbrain	midbrain dopaminergic neuron	Present		2B-1	Expressed in mesodiencephalic dopaminergic neurons.

2B-2 ©

Specimen 2B lateral to medial 2: embryonic day 12.5 (more

)
Note: Double labeled: brown - Th; blue - Nkx2-9 (assay MGI:7576004).

Structure	Cell Type	Level	Pattern	Image	Note
TS20: midbrain	midbrain dopaminergic neuron	Present		2B-2	Expressed in mesodiencephalic dopaminergic neurons.

2B-3 ©

Specimen 2B lateral to medial 3: embryonic day 12.5 (more

)
Note: Double labeled: brown - Th; blue - Nkx2-9 (assay MGI:7576004).

Structure	Cell Type	Level	Pattern	Image	Note
TS20: midbrain	midbrain dopaminergic neuron	Present		2B-3	Expressed in mesodiencephalic dopaminergic neurons.

2B-4 ©

Specimen 2B lateral to medial 4: embryonic day 12.5 (more

)
Note: Double labeled: brown - Th; blue - Nkx2-9 (assay MGI:7576004).

Structure	Cell Type	Level	Pattern	Image	Note
TS20: midbrain	midbrain dopaminergic neuron	Present		2B-4	Expressed in mesodiencephalic dopaminergic neurons.

2B-5 ©

Specimen 2B lateral to medial 5: embryonic day 12.5 (more

)
Note: Double labeled: brown - Th; blue - Nkx2-9 (assay MGI:7576004).

Structure	Cell Type	Level	Pattern	Image	Note
TS20: midbrain	midbrain dopaminergic neuron	Present		2B-5	Expressed in mesodiencephalic dopaminergic neurons.

2B-6 ©

Specimen 2B lateral to medial 6: embryonic day 12.5 (more

)
Note: Double labeled: brown - Th; blue - Nkx2-9 (assay MGI:7576004).

Structure	Cell Type	Level	Pattern	Image	Note
TS20: midbrain	midbrain dopaminergic neuron	Present		2B-6	Expressed in mesodiencephalic dopaminergic neurons.

2B-7 ©

Specimen 2B lateral to medial 7: embryonic day 12.5 (more

)
Note: Double labeled: brown - Th; blue - Nkx2-9 (assay MGI:7576004).

Structure	Cell Type	Level	Pattern	Image	Note
TS20: midbrain	midbrain dopaminergic neuron	Present		2B-7	Expressed in mesodiencephalic dopaminergic neurons.

6B +/+ upper ©

Specimen 6B +/+ rostral to caudal 1: postnatal month 2.5 (more

)

Structure	Cell Type	Level	Pattern	Image	Note
TS28: midbrain	midbrain dopaminergic neuron	Present		6B +/+ upper

6B +/+ middle ©

Specimen 6B +/+ rostral to caudal 2: postnatal month 2.5 (more

)

Structure	Cell Type	Level	Pattern	Image	Note
TS28: midbrain	midbrain dopaminergic neuron	Present		6B +/+ middle

6B +/+ lower ©

Specimen 6B +/+ rostral to caudal 3: postnatal month 2.5 (more

)

Structure	Cell Type	Level	Pattern	Image	Note
TS28: midbrain	midbrain dopaminergic neuron	Present		6B +/+ lower

6B LacZ/LacZ upper ©

Specimen 6B LacZ/LacZ rostral to caudal 1: postnatal month 2.5; Nkx2-9^tm1Jlck/Nkx2-9^tm1Jlck (more

)

Structure	Cell Type	Level	Pattern	Image	Note
TS28: midbrain	midbrain dopaminergic neuron	Present		6B LacZ/LacZ upper	Similar as in the wild-type.

6B LacZ/LacZ middle ©

Specimen 6B LacZ/LacZ rostral to caudal 2: postnatal month 2.5; Nkx2-9^tm1Jlck/Nkx2-9^tm1Jlck (more

)

Structure	Cell Type	Level	Pattern	Image	Note
TS28: midbrain	midbrain dopaminergic neuron	Present		6B LacZ/LacZ middle	Similar as in the wild-type.

6B LacZ/LacZ lower ©

Specimen 6B LacZ/LacZ rostral to caudal 3: postnatal month 2.5; Nkx2-9^tm1Jlck/Nkx2-9^tm1Jlck (more

)

Structure	Cell Type	Level	Pattern	Image	Note
TS28: midbrain	midbrain dopaminergic neuron	Present		6B LacZ/LacZ lower	Similar as in the wild-type.

6E +/+ ©

Specimen 6E +/+: postnatal month 2.5 (more

)

Structure	Cell Type	Level	Pattern	Image	Note
TS28: corpus striatum	midbrain dopaminergic neuron	Present		6E +/+

6E LacZ/LacZ ©

Specimen 6E LacZ/LacZ: postnatal month 2.5; Nkx2-9^tm1Jlck/Nkx2-9^tm1Jlck (more

)

Structure	Cell Type	Level	Pattern	Image	Note
TS28: corpus striatum	midbrain dopaminergic neuron	Present		6E LacZ/LacZ	Similar as in the wild-type.

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