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Gene Expression Data
Assay Details
Assay
Reference: J:293091 Li Z, et al., Neural progenitor cells mediated by H2A.Z.2 regulate microglial development via Cxcl14 in the embryonic brain. Proc Natl Acad Sci U S A. 2019 Nov 26;116(48):24122-24132
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7544067
Gene symbol: Arg1
Gene name: arginase, liver
Results
Specimen S6A fl/fl: embryonic day 16.5; H2az2tm1.1Hko/H2az2tm1.1Hko (more )
Note: Double labeled: green - Arg1; red - Aif1 (assay MGI:7544053).
Structure Cell Type Level Pattern Image Note
TS24: cerebral cortex microglial cell Present S6A fl/fl Arg1 , S6A fl/fl (merged)
Specimen S6A cKO: embryonic day 16.5; H2az2tm1.1Hko/H2az2tm1.1Hko, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant. Double labeled: green - Arg1; red - Aif1 (assay MGI:7544053).
Structure Cell Type Level Pattern Image Note
TS24: cerebral cortex microglial cell Present Regionally restricted S6A cKO Arg1 , S6A cKO (merged) Proportion of M2-type (Arg1+Aif1+) microglia significantly increased compared to control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/14/2024
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