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Gene Expression Data
Assay Details
Assay
Reference: J:336175 Fuchs MAA, et al., Intact prostaglandin signaling through EP2 and EP4 receptors in stromal progenitor cells is required for normal development of the renal cortex in mice. Am J Physiol Renal Physiol. 2022 Mar 1;322(3):F295-F307
Assay type: RNA in situ
MGI Accession ID: MGI:7531039
Gene symbol: Ptger2
Gene name: prostaglandin E receptor 2 (subtype EP2)
Probe: Mm-Ptger2 (456481)
Probe preparation: Antisense
Visualized with: Fluorescence
Assay notes: RNAscope assay.
Results
Specimen 2A (top): postnatal day 9 (more )
Note: Double labeled: red - Ptger2; green - Ren1 (assay MGI:7531042).
Structure Cell Type Level Pattern Image Note
TS28: glomerular tuft kidney granular cell Strong Regionally restricted 2A (top) Strong expression in renin-expressing cells at glomeruli.
Specimen 2A (middle): postnatal day 9 (more )
Note: Double labeled: red - Ptger2; green - Pdgfrb (assay MGI:7531043).
Structure Cell Type Level Pattern Image Note
TS28: glomerular mesangium glomerular mesangial cell Present Regionally restricted 2A (middle) Co-localization with Pdgfra in intraglomerular mesangial cells.
TS28: extraglomerular mesangium extraglomerular mesangial cell Present Regionally restricted 2A (middle) Co-localization with Pdgfra in extraglomerular mesangial cells.
Specimen 2A (bottom): postnatal day 9 (more )
Note: Double labeled: red - Ptger2; green - Pdgfrb (assay MGI:7531043).
Structure Cell Type Level Pattern Image Note
TS28: inner medullary interstitium kidney inner medulla interstitial cell Present 2A (bottom)
Specimen 3 (left): postnatal day 9 (more )
Note: Double labeled: red - Ptger2; blue - Aqp2 (assay MGI:7531046).
Structure Cell Type Level Pattern Image Note
TS28: inner medullary interstitium kidney inner medulla interstitial cell Present Regionally restricted 3_(left) Expression in interstitial cells associated with Aqp2-expressing tubules.
Specimen 5A (top): postnatal week 15 (more )
Note: Double labeled: red - Ptger2; green - Pdgfrb (assay MGI:7531043).
Structure Cell Type Level Pattern Image Note
TS28: extraglomerular mesangium extraglomerular mesangial cell Present Regionally restricted 5A (top) Expression in extraglomerular mesangial cells coexpressing Pdgfra.
Specimen 5A (bottom): postnatal week 15 (more )
Note: Double labeled: red - Ptger2; green - Pdgfrb (assay MGI:7531043).
Structure Cell Type Level Pattern Image Note
TS28: inner medullary interstitium kidney inner medulla interstitial cell Present Regionally restricted 5A (bottom) Expression in medullary interstitiial cells coexpressing Pdgfra.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory