Smad1 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:198483 Finelli MJ, et al., Differential phosphorylation of Smad1 integrates BMP and neurotrophin pathways through Erk/Dusp in axon development. Cell Rep. 2013 May 30;3(5):1592-606
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:7529719
Gene symbol:	Smad1
Gene name:	SMAD family member 1

Antibody:

anti-pSmad1L

Results

6A +/+ ©

Specimen 6A +/+: postnatal day 1 (more

)

Structure	Cell Type	Level	Pattern	Image	Note
TS27: dorsal root ganglion	sensory neuron of dorsal root ganglion	Present		6A +/+	Expression in nuclei of neurons from E12.5 to P1.

6A L/L ©

Specimen 6A L/L: postnatal day 1; Smad1^tm2Sor/Smad1^tm2Sor (more

)

Structure	Level	Pattern	Image	Note
TS27: dorsal root ganglion	Absent		6A L/L	Expression absent in mutant.

6B Control ©

Specimen 6B Control: postnatal day 1; Smad1^tm1Abr/Smad1⁺, Tg(Nes-cre)1Kln/0 (more

)
Note: Conditional mutant.

Structure	Cell Type	Level	Pattern	Image	Note
TS27: dorsal root ganglion	sensory neuron of dorsal root ganglion	Present		6B Control	Expression in nuclei of neurons from E12.5 to P1.

6B cKO ©

Specimen 6B cKO: postnatal day 1; Smad1^tm1Abr/Smad1^tm1.1Abr, Tg(Nes-cre)1Kln/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS27: dorsal root ganglion	Absent		6B cKO	Expression absent in mutant

S6F pSMAD1L ©

Specimen S6F pSmad1L: postnatal day 1 (more

)

Structure	Cell Type	Level	Pattern	Image	Note
TS27: peripheral nerve	Schwann cell	Absent		S6F pSMAD1L	No expression in Schwann cells.

S6G ©

Specimen S6G pSmad1L: postnatal day 1 (more

)
Note: Double labeled: red - Smad1; green - Tubb3 (assay MGI:7529721).

Structure	Cell Type	Level	Pattern	Image	Note
TS27: dorsal root ganglion	sensory neuron of dorsal root ganglion	Present		S6G	Expression only detectable in neurons.
TS27: peripheral nerve	Schwann cell	Absent		S6G	No expression in Schwann cells.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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