About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:92061 Eng SR, et al., Coordinated regulation of gene expression by Brn3a in developing sensory ganglia. Development. 2004 Aug;131(16):3859-70
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7521972
Gene symbol: Calb2
Gene name: calbindin 2
Results
Specimen 2F Calret +/+: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: trigeminal ganglion Present 2F Calret +/+
Specimen 2F Calret -/-: embryonic day 13.5; Pou4f1tm1Nat/Pou4f1tm1Nat (more )
Structure Level Pattern Image Note
TS21: trigeminal ganglion Strong 2F Calret -/- Expression markedly increased compared to control.
Specimen Calret +/+ not shown: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: dorsal root ganglion Present
TS21: spinal cord Present Regionally restricted Expression in dorsal spinal cord.
Specimen Calret -/- not shown: embryonic day 13.5; Pou4f1tm1Nat/Pou4f1tm1Nat (more )
Structure Level Pattern Image Note
TS21: dorsal root ganglion Present No significant changes in expression compared to control.
TS21: spinal cord Present Regionally restricted No change in expression in dorsal spinal cord compared to wild type.
Specimen 4A Calret: embryonic day 13.5 (more )
Note: Double labeled: green - Calb2; red - Pou4f1 (assay MGI:7521967).
Structure Level Pattern Image Note
TS21: hindbrain Present Regionally restricted 4A Expression characterize distinct populations of neurons - expression in adjacent but non-overlapping cell populations.
TS21: midbrain Present Regionally restricted 4A Expression characterize distinct populations of neurons - expression in adjacent but non-overlapping cell populations.
TS21: thalamus Present Regionally restricted 4A Expression characterize distinct populations of neurons - expression in adjacent but non-overlapping cell populations.
Specimen 4B Calret: embryonic day 13.5 (more )
Note: Double labeled: green - Calb2; red - Pou4f1 (assay MGI:7521967).
Structure Level Pattern Image Note
TS21: midbrain Present Regionally restricted 4B Authors report distinct expression of Calb2 and Pou4f1.
Specimen 4C Calret: embryonic day 13.5; Pou4f1tm1Nat/Pou4f1tm1Nat (more )
Note: Double labeled: green - Calb2; red - Pou4f1 (assay MGI:7521967).
Structure Level Pattern Image Note
TS21: midbrain Present 4C No apparent change in expression compared to control.
Specimen 4D/E Calret: embryonic day 13.5 (more )
Note: Double labeled: green - Calb2; red - Pou4f1 (assay MGI:7521967).
Structure Level Pattern Image Note
TS21: retina Present Regionally restricted 4E , 4D Expression overlapping with Pou4f1. Subset of neurons co-express both Calb2 and Pou4f1.
Specimen 4F Calret: embryonic day 13.5; Pou4f1tm1Nat/Pou4f1tm1Nat (more )
Note: Double labeled: green - Calb2; red - Pou4f1 (assay MGI:7521967).
Structure Level Pattern Image Note
TS21: retina Present 4F No apparent change in expression compared to control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory