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Gene Expression Data
Assay Details
Assay
Reference: J:324832 Sun Y, et al., Single-cell transcriptomic landscapes of the otic neuronal lineage at multiple early embryonic ages. Cell Rep. 2022 Mar 22;38(12):110542
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7493756
Gene symbol: Sox2
Gene name: SRY (sex determining region Y)-box 2
Antibody: Anti-Sox2 (Y-17; sc-17320)
Detection system: Secondary antibody
Assay notes: The authors reporting using two anti-Sox2 antibodies; it is possible MGI:5762877 was used to derive these data.
Results
Specimen 4F: embryonic day 12.5; Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Myt1tm1(EGFP/icre)Ldh/Myt1+ (more )
Note: Conditional mutant. Multi-labeled: white - Sox2; green - Myt1 reporter (assay MGI:7493750); red - Cre reporter; blue - Hoechst.
Structure Cell Type Level Pattern Image Note
TS21: cochlear ganglion glial cell Present 4F''' , 4F''
Specimen 4H: embryonic day 15.5 (more )
Note: Multi-labeled: red - Sox2; green - Myt1 (assay MGI:7493605); white - Tubb3 (assay MGI:7493858); blue - Hoechst.
Structure Cell Type Level Pattern Image Note
TS23: cochlear ganglion glial cell Present 4H'' , 4H'''
Specimen S4D: embryonic day 11.5; Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Tg(Tlx3-cre)PL56Gsat/0 (more )
Note: Conditional mutant. Multi-labeled: white - Sox2; green - Phox2b (assay MGI:7493529); red - Cre reporter; blue - Hoechst.
Structure Level Pattern Image Note
TS20: vestibulo-cochlear ganglion Present S4D''' , S4D' , S4E Expression is seen in undifferentiated cochleo-vestibular ganglions.
Specimen S6C: embryonic day 13.5; Foxg1tm1.1(cre)Ddmo/Foxg1+, Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Multi-labeled: white - Sox2; green - Otx2 (assay MGI:7493871); red - Cre reporter; blue - Hoechst.
Structure Level Pattern Image Note
TS22: cochlea Present S6C''' , S6C''
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory