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Gene Expression Data
Assay Details
Assay
Reference: J:324832 Sun Y, et al., Single-cell transcriptomic landscapes of the otic neuronal lineage at multiple early embryonic ages. Cell Rep. 2022 Mar 22;38(12):110542
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7493531
Gene symbol: Insm1
Gene name: insulinoma-associated 1
Antibody: anti-Insm1
Detection system: Secondary antibody
Results
Specimen S2C: embryonic day 9.5; Foxg1tm1.1(cre)Ddmo/Foxg1+, Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Triple labeled: green - Insm1; red - Cre reporter; blue - Hoechst.
Structure Level Pattern Image Note
TS16: cranial ganglion Present Regionally restricted S2D , S2D' Expression is seen in cells committed to be cochleo-vestibular ganglion cells.
Specimen 3E/F: embryonic day 11.5; Foxg1tm1.1(cre)Ddmo/Foxg1+, Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Multi-labeled: green - Insm1; white - Myt1 (assay MGI:7493605); red - Cre reporter; blue - Hoechst.
Structure Level Pattern Image Note
TS20: vestibulo-cochlear ganglion Present 3E' , 3F''' , 3E''' , 3F'
Specimen 4A/B: embryonic day 9.5 (more )
Note: Multi-labeled: green - Insm1; red - Myt1 (assay MGI:7493605); white - Neurod1 (assay MGI:7493524); blue - Hoechst.
Structure Level Pattern Image Note
TS16: cranial ganglion Present Regionally restricted 4B''' , 4A''' , 4B , 4A Expression is seen in cells committed to be cochleo-vestibular ganglion cells.
Specimen 5E: embryonic day 13.5; Foxg1tm1.1(cre)Ddmo/Foxg1+, Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Multi-labeled: white - Insm1; green - Myt1 (assay MGI:7493605); red - Cre reporter; blue - Hoechst.
Structure Cell Type Level Pattern Image Note
TS22: vestibular ganglion neuron Present Non-Uniform 5F''' , 5E''' , 5F'' , 5E'' Expression is stronger in inferior vestibular ganglion cells than superior ones.
Specimen S6D: embryonic day 13.5; Foxg1tm1.1(cre)Ddmo/Foxg1+, Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Multi-labeled: white - Insm1; green - Myt1 (assay MGI:7493605); red - Cre reporter; blue - Hoechst.
Structure Cell Type Level Pattern Image Note
TS22: cochlear ganglion neuron Present S6D' , S6D'''
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory