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Gene Expression Data
Assay Details
Assay
Reference: J:309377 Betterman KL, et al., Atypical cadherin FAT4 orchestrates lymphatic endothelial cell polarity in response to flow. J Clin Invest. 2020 Jun 1;130(6):3315-3328
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7486753
Gene symbol: Nrp2
Gene name: neuropilin 2
Antibody: Anti-Neuropilin 2 (AF2215)
Detection system: Secondary antibody coupled to Alexa Fluor
Assay notes: Two Nrp2 antibodies were described, MGI:7486740 and MGI:7486745; the antibody used in this assay was not specified.
Results
Specimen 2B: embryonic day 14.5 (more )
Note: Double labeled: cyan - Nrp2; red - Prox1 (assay MGI:7486752).
Structure Cell Type Level Pattern Image Note
TS22: lymphatic vessel endothelial cell of lymphatic vessel Present Regionally restricted 2B Expression was detected on the lymphatic endothelial cell surface in dorsal skin lymphatic vessels.

Specimen 2E: embryonic day 14.5; Fat4tm1Hmc/Fat4tm1Hmc, Tg(CMV-cre)1Cgn/0 (more )
Note: Conditional mutant. Double labeled: cyan - Nrp2; red - Prox1 (assay MGI:7486752).
Structure Cell Type Level Pattern Image Note
TS22: lymphatic vessel endothelial cell of lymphatic vessel Present Regionally restricted 2E Expression was detected on the lymphatic endothelial cell surface in dorsal skin lymphatic vessels, which were wider in the mutant than in control.

Specimen S5A: embryonic day 14.5 (more )
Note: Double labeled: cyan - Nrp2; red - PH3.
Structure Cell Type Level Pattern Image Note
TS22: lymphatic vessel endothelial cell of lymphatic vessel Present Regionally restricted S5A Expression was detected on the lymphatic endothelial cell surface in dorsal skin lymphatic vessels.

Specimen S5B: embryonic day 14.5; Fat4tm1Hmc/Fat4tm1Hmc, Tg(CMV-cre)1Cgn/0 (more )
Note: Conditional mutant. Double labeled: cyan - Nrp2; red - PH3.
Structure Cell Type Level Pattern Image Note
TS22: lymphatic vessel endothelial cell of lymphatic vessel Present Regionally restricted S5B Expression was detected on the lymphatic endothelial cell (LEC) surface in dorsal skin lymphatic vessels.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory