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Gene Expression Data
Assay Details
Assay
Reference: J:126484 Luo W, et al., A hierarchical NGF signaling cascade controls Ret-dependent and Ret-independent events during development of nonpeptidergic DRG neurons. Neuron. 2007 Jun 7;54(5):739-54
Assay type: RNA in situ
MGI Accession ID: MGI:7481265
Gene symbol: Ntrk1
Gene name: neurotrophic tyrosine kinase, receptor, type 1
Probe: TrkA probe
Probe preparation: labelled with fluorescein RNA
Results
Specimen 1A E12: embryonic day 12.0 (more )
Note: Double labeled: red - TrkA (Ntrk1); green - Ret (assay MGI:7481266).
Structure Cell Type Level Pattern Image Note
TS20: dorsal root ganglion sensory neuron of dorsal root ganglion Present Widespread 1A E12 Widespread expression in majority of neurons.
Specimen 1A E16: embryonic day 16.0 (more )
Note: Double labeled: red - TrkA (Ntrk1); green - Ret (assay MGI:7481266).
Structure Cell Type Level Pattern Image Note
TS24: dorsal root ganglion sensory neuron of dorsal root ganglion Present Widespread 1A E16 From E16 to P0, expression in neurons. Many neurons begin to coexpress Ret.
Specimen 1A P0: postnatal day 0 (more )
Note: Double labeled: red - TrkA (Ntrk1); green - Ret (assay MGI:7481266).
Structure Cell Type Level Pattern Image Note
TS27: dorsal root ganglion sensory neuron of dorsal root ganglion Present Widespread 1A P0 From E16 to P0, expression in neurons. Many neurons begin to coexpress Ret.
Specimen 1A P5: postnatal day 5 (more )
Note: Double labeled: red - TrkA (Ntrk1); green - Ret (assay MGI:7481266).
Structure Cell Type Level Pattern Image Note
TS28: dorsal root ganglion sensory neuron of dorsal root ganglion Present Regionally restricted 1A P5 Expression extinguished in Ret-expressing neurons after birth.
Specimen 1A P10: postnatal day 10 (more )
Note: Double labeled: red - TrkA (Ntrk1); green - Ret (assay MGI:7481266).
Structure Cell Type Level Pattern Image Note
TS28: dorsal root ganglion sensory neuron of dorsal root ganglion Present Regionally restricted 1A P10 Expression extinguished in Ret-expressing neurons after birth.
Specimen 1A P14: postnatal day 14 (more )
Note: Double labeled: red - TrkA (Ntrk1); green - Ret (assay MGI:7481266).
Structure Cell Type Level Pattern Image Note
TS28: dorsal root ganglion sensory neuron of dorsal root ganglion Present Regionally restricted 1A P14 Segregation of neurons expressing TrkA from those expressing Ret nearly complete.
Specimen S2B: postnatal day 0; Baxtm1Sjk/Baxtm1Sjk, Ngftm1Gne/Ngf+ (more )
Note: Double labeled: red - TrkA (Ntrk1); green - Ret (assay MGI:7481266).
Structure Level Pattern Image Note
TS27: dorsal root ganglion Present Widespread S2B TrkA , S2B Overlay
Specimen S2C: postnatal day 0; Baxtm1Sjk/Baxtm1Sjk, Ngftm1Gne/Ngftm1Gne (more )
Note: Double labeled: red - TrkA (Ntrk1); green - Ret (assay MGI:7481266).
Structure Level Pattern Image Note
TS27: dorsal root ganglion Present S2C Overlay , S2C TrkA
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/14/2024
MGI 6.23 		The Jackson Laboratory