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Gene Expression Data
Assay Details
Assay
Reference: J:237224 Kim JY, et al., Yap is essential for retinal progenitor cell cycle progression and RPE cell fate acquisition in the developing mouse eye. Dev Biol. 2016 Nov 15;419(2):336-347
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7437601
Gene symbol: Vsx2
Gene name: visual system homeobox 2
Antibody: anti-Chx10 (X1179P)
Detection system: Secondary antibody coupled to Cy5
Results
Specimen 4E: embryonic day 16.5; Yap1tm1.1Eno/Yap1tm1.1Eno (more )
Structure Cell Type Level Pattern Image Note
TS24: neural retina retinal progenitor cell Present 4E
TS24: pigmented retinal epithelium Absent 4E
Specimen 4F: embryonic day 16.5; Tg(rx3-icre)1Mjam/0, Yap1tm1.1Eno/Yap1tm1.1Eno (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS24: pigmented retinal epithelium Present Regionally restricted 4F Ectopic expression was seen in the abnormal multi-cell layered region.
TS24: neural retina retinal progenitor cell Present 4F
Specimen S4A: embryonic day 16.5; Yap1tm1.1Eno/Yap1tm1.1Eno (more )
Note: Double labeled: red - Vsx2; green - Yap1 (assay MGI:7437575).
Structure Cell Type Level Pattern Image Note
TS24: neural retina retinal progenitor cell Present S4A
Specimen S4B: embryonic day 16.5; Tg(rx3-icre)1Mjam/0, Yap1tm1.1Eno/Yap1tm1.1Eno (more )
Note: Conditional mutant. Double labeled: red - Vsx2; green - Yap1 (assay MGI:7437575).
Structure Cell Type Level Pattern Image Note
TS24: neural retina retinal progenitor cell Present S4B Similar as in the wild-type.
Specimen S4C: postnatal day 0; Yap1tm1.1Eno/Yap1tm1.1Eno (more )
Note: Double labeled: red - Vsx2; green - Yap1 (assay MGI:7437575).
Structure Cell Type Level Pattern Image Note
TS27: neural retina retinal progenitor cell Present S4C
Specimen S4D: postnatal day 0; Tg(rx3-icre)1Mjam/0, Yap1tm1.1Eno/Yap1tm1.1Eno (more )
Note: Conditional mutant. Double labeled: red - Vsx2; green - Yap1 (assay MGI:7437575).
Structure Cell Type Level Pattern Image Note
TS27: neural retina retinal progenitor cell Present S4D Similar as in the wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/28/2024
MGI 6.13 		The Jackson Laboratory