About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:333013 Huang T, et al., Direct Interaction of Sox10 With Cadherin-19 Mediates Early Sacral Neural Crest Cell Migration: Implications for Enteric Nervous System Development Defects. Gastroenterology. 2022 Jan;162(1):179-192.e11
Assay type: RNA in situ
MGI Accession ID: MGI:7434135
Gene symbol: Sox10
Gene name: SRY (sex determining region Y)-box 10
Probe: Sox10 probe34
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 3B Sox10: embryonic day 9.5 (more )
Note: Double labeled: red - Sox10; green - Cdh19 (assay MGI:7434133).
Structure Cell Type Level Pattern Image Note
TS15: neural crest migratory neural crest cell Present Regionally restricted 3Biii , 3Bv , 3Bii , 3Bvi inset , 3Bvi , 3Bv inset Co-localization with Cdh19 expression in sacral neural crest cells delaminating from neural tube.
Specimen 3C Sox10: embryonic day 11.5 (more )
Note: Double labeled: red - Sox10; green - Cdh19 (assay MGI:7434133).
Structure Cell Type Level Pattern Image Note
TS19: migrating neural crest migratory neural crest cell Present Regionally restricted 3Cii , 3Ciii Co-localization with Cdh19 expression in sacral neural crest cells along medial migration pathway.
TS19: dorsal root ganglion Present 3Cv , 3Cvi Co-localization with Cdh19 expression in in dorsal root ganglia and sympathetic ganglia.
TS19: sympathetic ganglion Present 3Cv , 3Cvi Co-localization with Cdh19 expression in in dorsal root ganglia and sympathetic ganglia.
TS19: pelvic ganglion Present 3Cviii , 3Cix Co-localization with Cdh19 expression in pelvic ganglia.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory