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Gene Expression Data
Assay Details
Assay
Reference: J:242348 Soh YQS, et al., Meioc maintains an extended meiotic prophase I in mice. PLoS Genet. 2017 Apr;13(4):e1006704
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7428714
Gene symbol: Sycp3
Gene name: synaptonemal complex protein 3
Results
Specimen 3B P15 Wild-type: postnatal day 15 (more )
Note: The genetic background of specimens labeled Wild-type was either wild type or heterozygous. Triple labeled: green - Sycp3; red - Dmc1 (assay MGI:7428713); blue - MVH (Ddx4 assay MGI:7428709).
Structure Level Pattern Image Note
TS28: germ cell of testis Present Regionally restricted 3B P15 Wild-type SYCP3 , 3B P15 Wild-type Expression localized along chromosomes in germ cells at various stages of meiotic prophase.
Specimen 3B P15 Meioc-/-: postnatal day 15; Meioctm1.1Dcp/Meioctm1.1Dcp (more )
Note: Triple labeled: green - Sycp3; red - Dmc1 (assay MGI:7428713); blue - MVH (Ddx4 assay MGI:7428709).
Structure Level Pattern Image Note
TS28: germ cell of testis Present Regionally restricted 3B P15 Meioc-/- SYCP3 , 3B P15 Meioc-/- Pattern of expression does not progress beyond what is typical of early zygotene. Some germ cells containing only aggregates.
Specimen 3B E16.5 Wild-type: embryonic day 16.5 (more )
Note: The genetic background of specimens labeled Wild-type was either wild type or heterozygous. Triple labeled: green - Sycp3; red - Dmc1 (assay MGI:7428713); blue - MVH (Ddx4 assay MGI:7428709).
Structure Level Pattern Image Note
TS24: germ cell of ovary Present Regionally restricted 3B E16.5 Wild-type , 3B E16.5 Wild-type SYCP3 Expression consistent with germ cells at pachytene stage.
Specimen 3B E16.5 Meioc-/-: embryonic day 16.5; Meioctm1.1Dcp/Meioctm1.1Dcp (more )
Note: Triple labeled: green - Sycp3; red - Dmc1 (assay MGI:7428713); blue - MVH (Ddx4 assay MGI:7428709).
Structure Level Pattern Image Note
TS24: germ cell of ovary Present Regionally restricted 3B E16.5 Meioc-/- , 3B E16.5 Meioc-/- SYCP3 Pattern of expression does not progress beyond what is typical of early zygotene. Some germ cells containing only aggregates.
Specimen 5A Wild-type: postnatal day 15 (more )
Note: The genetic background of specimens labeled Wild-type was either wild type or heterozygous. Double labeled: red - Sycp3; green - Ccna2 (assay MGI:7428717).
Structure Level Pattern Image Note
TS28: germ cell of testis Present Regionally restricted 5A Wild-type (merge) , 5A Wild-type SYCP3 Expression in germ cells at zygotene stage.
Specimen 5A Meioc-/-: postnatal day 15; Meioctm1.1Dcp/Meioctm1.1Dcp (more )
Note: Double labeled: red - Sycp3; green - Ccna2 (assay MGI:7428717).
Structure Level Pattern Image Note
TS28: germ cell of testis Present Regionally restricted 5A Meioc-/- (merge) , 5A Meioc-/- SYCP3
Specimen 6B Wild-type: postnatal day 15 (more )
Note: The genetic background of specimens labeled Wild-type was either wild type or heterozygous. Double labeled: green - Sycp3; red - Ythdc2 (assay MGI:7428718).
Structure Level Pattern Image Note
TS28: germ cell of testis Present Regionally restricted 6B Wild-type Expression in zygotene and zygotene-like germ cells.
Specimen 6B Meioc-/-: postnatal day 15; Meioctm1.1Dcp/Meioctm1.1Dcp (more )
Note: Double labeled: green - Sycp3; red - Ythdc2 (assay MGI:7428718).
Structure Level Pattern Image Note
TS28: germ cell of testis Present Regionally restricted 6B Meioc-/- Expression in zygotene and zygotene-like germ cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/28/2024
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