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Gene Expression Data
Assay Details
Assay
Reference: J:331477 Bhalla P, et al., Mesenchymal cell replacement corrects thymic hypoplasia in murine models of 22q11.2 deletion syndrome. J Clin Invest. 2022 Nov 15;132(22)
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7398232
Gene symbol: Mcam
Gene name: melanoma cell adhesion molecule
Results
Specimen 6B Mcam +/+: embryonic day 13.0-13.5 (more )
Note: Multi-labeled: purple - Mcam; red - Pecam1 (CD31; assay MGI:7398230) and Emcn (assay MGI:7398233); green - Cspg4 (assay MGI:7398231).
Structure Level Pattern Image Note
TS21: thymus primordium Present Regionally restricted 6B +/+ (row 1) , 6B +/+ (row 3) Expression in extracellular matrix.
Specimen 6B Mcam +/neo2: embryonic day 13.0-13.5; Tbx1tm5Bld/Tbx1+ (more )
Note: Multi-labeled: purple - Mcam; red - Pecam1 (CD31; assay MGI:7398230) and Emcn (assay MGI:7398233); green - Cspg4 (assay MGI:7398231).
Structure Level Pattern Image Note
TS21: thymus primordium Strong Regionally restricted 6B +/neo2 (row 1) , 6B +/neo2 (row 3) Higher levels of expression than in controls.
Specimen 6B Mcam neo2/neo2: embryonic day 13.0-13.5; Tbx1tm5Bld/Tbx1tm5Bld (more )
Note: Multi-labeled: purple - Mcam; red - Pecam1 (CD31; assay MGI:7398230) and Emcn (assay MGI:7398233); green - Cspg4 (assay MGI:7398231).
Structure Level Pattern Image Note
TS21: thymus primordium Strong Regionally restricted 6B neo2/neo2 (row 1) , 6B neo2/neo2 (row 3) Higher levels of expression than in controls.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory