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Gene Expression Data
Assay Details
Assay
Reference: J:331477 Bhalla P, et al., Mesenchymal cell replacement corrects thymic hypoplasia in murine models of 22q11.2 deletion syndrome. J Clin Invest. 2022 Nov 15;132(22)
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7398230
Gene symbol: Pecam1
Gene name: platelet/endothelial cell adhesion molecule 1
Antibody: MEC 13.3
Results
Specimen 6A CD31 +/+: embryonic day 13.0-13.5 (more )
Note: Double labeled: red - Pecam1 (CD31); green - Col1a1 (assay MGI:7398229).
Structure Level Pattern Image Note
TS21: thymus primordium Present Regionally restricted 6A +/+ (middle) , 6A +/+ (top) Expression in vascular endothelium.
Specimen 6A CD31 +/neo2: embryonic day 13.0-13.5; Tbx1tm5Bld/Tbx1+ (more )
Note: Double labeled: red - Pecam1 (CD31); green - Col1a1 (assay MGI:7398229).
Structure Level Pattern Image Note
TS21: thymus primordium Present Regionally restricted 6A +/neo2 (middle) , 6A +/neo2 (top) Expression in vascular endothelium.
Specimen 6A CD31 neo2/neo2 e.g.1: embryonic day 13.0-13.5; Tbx1tm5Bld/Tbx1tm5Bld (more )
Note: Double labeled: red - Pecam1 (CD31); green - Col1a1 (assay MGI:7398229).
Structure Level Pattern Image Note
TS21: thymus primordium Present Regionally restricted 6A neo2/neo2 e.g.1 (top) , 6A neo2/neo2 e.g.1 (middle) Expression in vasculature resembled that of controls.
Specimen 6A CD31 neo2/neo2 e.g.2: embryonic day 13.0-13.5; Tbx1tm5Bld/Tbx1tm5Bld (more )
Note: Double labeled: red - Pecam1 (CD31); green - Col1a1 (assay MGI:7398229).
Structure Level Pattern Image Note
TS21: thymus primordium Present Regionally restricted 6A neo2/neo2 e.g.2 (middle) , 6A neo2/neo2 e.g.2 (top) Expression in vasculature resembled that of controls.
Specimen 6B CD31 +/+: embryonic day 13.0-13.5 (more )
Note: Multi-labeled: red - CD31 (Pecam1) and Emcn (assay MGI:7398233); green - Cspg4 (assay MGI:7398231); purple - Mcam (assay MGI:7).
Structure Level Pattern Image Note
TS21: thymus primordium Present Regionally restricted 6B +/+ (row 1) , 6B +/+ (row 4) Expression in vascular endothelium.
Specimen 6B CD31 +/neo2: embryonic day 13.0-13.5; Tbx1tm5Bld/Tbx1+ (more )
Note: Multi-labeled: red - CD31 (Pecam1) and Emcn (assay MGI:7398233); green - Cspg4 (assay MGI:7398231); purple - Mcam (assay MGI:7).
Structure Level Pattern Image Note
TS21: thymus primordium Present Regionally restricted 6B +/neo2 (row 4) , 6B +/neo2 (row 1) Expression in vascular endothelium.
Specimen 6B CD31 neo2/neo2: embryonic day 13.0-13.5; Tbx1tm5Bld/Tbx1tm5Bld (more )
Note: Multi-labeled: red - CD31 (Pecam1) and Emcn (assay MGI:7398233); green - Cspg4 (assay MGI:7398231); purple - Mcam (assay MGI:7).
Structure Level Pattern Image Note
TS21: thymus primordium Present Regionally restricted 6B neo2/neo2 (row 1) , 6B neo2/neo2 (row 4) Expression in vascular endothelium.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory