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Gene Expression Data
Assay Details
Assay
Reference: J:331477 Bhalla P, et al., Mesenchymal cell replacement corrects thymic hypoplasia in murine models of 22q11.2 deletion syndrome. J Clin Invest. 2022 Nov 15;132(22)
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7398229
Gene symbol: Col1a1
Gene name: collagen, type I, alpha 1
Antibody: anti-Collagen I (ab21286)
Assay notes: Two antibodies were described, but the one used in this assay was not detailed. Anti-Collagen I MGI:7398215 may have been used in this assay.
Results
Specimen 6A Collagen +/+: embryonic day 13.0-13.5 (more )
Note: Double labeled: green - Col1a1; red - Pecam1 (CD31; assay MGI:7398230).
Structure Level Pattern Image Note
TS21: thymus primordium Present 6A +/+ (top) , 6A +/+ (bottom)

Specimen 6A Collagen +/neo2: embryonic day 13.0-13.5; Tbx1tm5Bld/Tbx1+ (more )
Note: Double labeled: green - Col1a1; red - Pecam1 (CD31; assay MGI:7398230).
Structure Level Pattern Image Note
TS21: thymus primordium Present 6A +/neo2 (top) , 6A +/neo2 (bottom)

Specimen 6A Collagen neo2/neo2 e.g.1: embryonic day 13.0-13.5; Tbx1tm5Bld/Tbx1tm5Bld (more )
Note: Double labeled: green - Col1a1; red - Pecam1 (CD31; assay MGI:7398230).
Structure Level Pattern Image Note
TS21: thymus primordium Present 6A neo2/neo2 e.g.1 (bottom) , 6A neo2/neo2 e.g.1 (top)

Specimen 6A Collagen neo2/neo2 e.g.2: embryonic day 13.0-13.5; Tbx1tm5Bld/Tbx1tm5Bld (more )
Note: Double labeled: green - Col1a1; red - Pecam1 (CD31; assay MGI:7398230).
Structure Level Pattern Image Note
TS21: thymus primordium Present 6A neo2/neo2 e.g.2 (bottom) , 6A neo2/neo2 e.g.2 (top)


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/22/2024
MGI 6.24
The Jackson Laboratory