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Gene Expression Data
Assay Details
Assay
Reference: J:328556 Sunny SS, et al., Multiple roles of Pax6 in postnatal cornea development. Dev Biol. 2022 Aug 29;491:1-12
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7397248
Gene symbol: Pax6
Gene name: paired box 6
Antibody: anti-Pax6 (#PRB-278P; #30130)
Detection system: Secondary antibody
Results
Specimen 1A: postnatal day 21; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz (more )
Structure Level Pattern Image Note
TS28: cornea epithelium Strong 1A
TS28: lens epithelium Strong 1A

Specimen 1A': postnatal day 21; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz, Tg(Aldh3a1-cre)1Zkoz/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: lens epithelium Present 1A'
TS28: cornea epithelium Present Regionally restricted 1A' Expression was absent or in a few cells in the central cornea (shown) and at the end of the peripheral cornea.

Specimen 1B: postnatal day 21; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz (more )
Structure Level Pattern Image Note
TS28: cornea epithelium Strong 1B
TS28: lens epithelium Strong 1B

Specimen 1B': postnatal day 21; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz, Tg(Aldh3a1-cre)1Zkoz/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: lens epithelium Present 1B'
TS28: cornea epithelium Present Regionally restricted 1B' Expression is at the end of the peripheral cornea (shown) and was absent or in a few cells in the central cornea.

Specimen 1C: postnatal day 28; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz (more )
Structure Level Pattern Image Note
TS28: cornea epithelium Strong 1C
TS28: lens epithelium Strong 1C

Specimen 1C': postnatal day 28; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz, Tg(Aldh3a1-cre)1Zkoz/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: lens epithelium Present 1C'
TS28: cornea epithelium Present Regionally restricted 1C' Expression was in a patch of cells at the central cornea (shown) and was absent in the peripheral cornea except for the very end.

Specimen 1D: postnatal day 28; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz (more )
Structure Level Pattern Image Note
TS28: cornea epithelium Strong 1D
TS28: lens epithelium Strong 1D

Specimen 1D': postnatal day 28; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz, Tg(Aldh3a1-cre)1Zkoz/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: lens epithelium Present 1D'
TS28: cornea epithelium Present Regionally restricted 1D' Expression was in a patch of cells at the central cornea and was absent in the peripheral cornea (shown) except for the end of the peripheral cornea.

Specimen 2A: postnatal day 21; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz (more )
Note: Double labeled: green - Pax6; red - Krt12 (assay MGI:7397269).
Structure Level Pattern Image Note
TS28: cornea epithelium Present 2A

Specimen 2A': postnatal day 21; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz, Tg(Aldh3a1-cre)1Zkoz/0 (more )
Note: Conditional mutant. Double labeled: green - Pax6; red - Krt12 (assay MGI:7397269).
Structure Level Pattern Image Note
TS28: cornea epithelium Present Regionally restricted 2A' Expression was absent or in a few cells in the central cornea (shown) and at the end of the peripheral cornea.

Specimen 2B: postnatal day 21; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz (more )
Note: Double labeled: green - Pax6; red - Krt12 (assay MGI:7397269).
Structure Level Pattern Image Note
TS28: cornea epithelium Present 2B

Specimen 2B': postnatal day 21; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz, Tg(Aldh3a1-cre)1Zkoz/0 (more )
Note: Conditional mutant. Double labeled: green - Pax6; red - Krt12 (assay MGI:7397269).
Structure Level Pattern Image Note
TS28: cornea epithelium Present Regionally restricted 2B' Expression is at the end of the peripheral cornea (shown) and was absent or in a few cells in the central cornea.

Specimen 2C: postnatal day 21; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz (more )
Note: Double labeled: green - Pax6; red - Krt14 (assay MGI:7397270).
Structure Level Pattern Image Note
TS28: cornea epithelium Present 2C

Specimen 2C': postnatal day 21; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz, Tg(Aldh3a1-cre)1Zkoz/0 (more )
Note: Conditional mutant. Double labeled: green - Pax6; red - Krt14 (assay MGI:7397270).
Structure Level Pattern Image Note
TS28: cornea epithelium Present Regionally restricted 2C' Expression was absent or in a few cells in the central cornea (shown) and at the end of the peripheral cornea.

Specimen 2D: postnatal day 21; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz (more )
Note: Double labeled: green - Pax6; red - Krt14 (assay MGI:7397270).
Structure Level Pattern Image Note
TS28: cornea epithelium Present 2D

Specimen 2D': postnatal day 21; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz, Tg(Aldh3a1-cre)1Zkoz/0 (more )
Note: Conditional mutant. Double labeled: green - Pax6; red - Krt14 (assay MGI:7397270).
Structure Level Pattern Image Note
TS28: cornea epithelium Present Regionally restricted 2D' Expression is at the end of the peripheral cornea (shown) and was absent or in a few cells in the central cornea.

Specimen 2E: postnatal day 21; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz (more )
Note: Double labeled: green - Pax6; red - Krt4 (assay MGI:7397276).
Structure Level Pattern Image Note
TS28: cornea epithelium Present 2E

Specimen 2E': postnatal day 21; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz, Tg(Aldh3a1-cre)1Zkoz/0 (more )
Note: Conditional mutant. Double labeled: green - Pax6; red - Krt4 (assay MGI:7397276).
Structure Level Pattern Image Note
TS28: cornea epithelium Present Regionally restricted 2E' Expression was absent or in a few cells in the central cornea (shown) and at the end of the peripheral cornea.

Specimen 2F: postnatal day 21; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz (more )
Note: Double labeled: green - Pax6; red - Krt4 (assay MGI:7397276).
Structure Level Pattern Image Note
TS28: cornea epithelium Present 2F

Specimen 2F': postnatal day 21; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz, Tg(Aldh3a1-cre)1Zkoz/0 (more )
Note: Conditional mutant. Double labeled: green - Pax6; red - Krt4 (assay MGI:7397276).
Structure Level Pattern Image Note
TS28: cornea epithelium Present Regionally restricted 2F' Expression is at the end of the peripheral cornea (shown) and was absent or in a few cells in the central cornea.

Specimen 2G: postnatal day 35; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz (more )
Note: Double labeled: green - Pax6; red - Krt10 (assay MGI:7397271).
Structure Level Pattern Image Note
TS28: cornea epithelium Present 2G

Specimen 2G': postnatal day 35; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz, Tg(Aldh3a1-cre)1Zkoz/0 (more )
Note: Conditional mutant. Double labeled: green - Pax6; red - Krt10 (assay MGI:7397271).
Structure Level Pattern Image Note
TS28: cornea epithelium Present Regionally restricted 2G' Expression was in a patch of cells at the central cornea and was absent in the peripheral cornea (shown) except for the end of the peripheral cornea.

Specimen 2H: postnatal day 35; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz (more )
Note: Double labeled: green - Pax6; red - Krt10 (assay MGI:7397271).
Structure Level Pattern Image Note
TS28: cornea epithelium Present 2H

Specimen 2H': postnatal day 35; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz, Tg(Aldh3a1-cre)1Zkoz/0 (more )
Note: Conditional mutant. Double labeled: green - Pax6; red - Krt10 (assay MGI:7397271).
Structure Level Pattern Image Note
TS28: cornea epithelium Present Regionally restricted 2H' Expression was in a patch of cells at the central cornea and was absent in the peripheral cornea except for the end of the peripheral cornea (shown).

Specimen 3A: postnatal day 21; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz (more )
Note: Double labeled with BrdU (red).
Structure Level Pattern Image Note
TS28: cornea epithelium Present 3A

Specimen 3A': postnatal day 21; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz, Tg(Aldh3a1-cre)1Zkoz/0 (more )
Note: Conditional mutant. Double labeled with BrdU (red).
Structure Level Pattern Image Note
TS28: cornea epithelium Present Regionally restricted 3A' Expression was in a patch of cells at the central cornea and was absent in the peripheral cornea except for the very end.

Specimen 3B: postnatal day 21; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz (more )
Note: Double labeled with BrdU (red).
Structure Level Pattern Image Note
TS28: cornea epithelium Present 3B

Specimen 3B': postnatal day 21; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz, Tg(Aldh3a1-cre)1Zkoz/0 (more )
Note: Conditional mutant. Double labeled with BrdU (red).
Structure Level Pattern Image Note
TS28: cornea epithelium Present Regionally restricted 3B' Expression was in a patch of cells at the central cornea and was absent in the peripheral cornea except for the very end.

Specimen 3C: postnatal day 21; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz (more )
Note: Double labeled with BrdU (red).
Structure Level Pattern Image Note
TS28: cornea epithelium Present 3C

Specimen 3C': postnatal day 21; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz, Tg(Aldh3a1-cre)1Zkoz/0 (more )
Note: Conditional mutant. Double labeled with BrdU (red).
Structure Level Pattern Image Note
TS28: cornea epithelium Present Regionally restricted 3C' Expression was in a patch of cells at the central cornea and was absent in the peripheral cornea except for the very end.

Specimen 3D: postnatal day 28; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz (more )
Note: Double labeled with BrdU (red).
Structure Level Pattern Image Note
TS28: cornea epithelium Present 3D

Specimen 3D': postnatal day 28; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz, Tg(Aldh3a1-cre)1Zkoz/0 (more )
Note: Conditional mutant. Double labeled with BrdU (red).
Structure Level Pattern Image Note
TS28: cornea epithelium Present Regionally restricted 3D' Expression was in a patch of cells at the central cornea and was absent in the peripheral cornea except for the very end.

Specimen 3E: postnatal day 28; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz (more )
Note: Double labeled with BrdU (red).
Structure Level Pattern Image Note
TS28: cornea epithelium Present 3E

Specimen 3E': postnatal day 28; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz, Tg(Aldh3a1-cre)1Zkoz/0 (more )
Note: Conditional mutant. Double labeled with BrdU (red).
Structure Level Pattern Image Note
TS28: cornea epithelium Present Regionally restricted 3E' Expression was in a patch of cells at the central cornea and was absent in the peripheral cornea except for the very end.

Specimen 3F: postnatal day 28; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz (more )
Note: Double labeled with BrdU (red).
Structure Level Pattern Image Note
TS28: cornea epithelium Present 3F

Specimen 3F': postnatal day 28; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz, Tg(Aldh3a1-cre)1Zkoz/0 (more )
Note: Conditional mutant. Double labeled with BrdU (red).
Structure Level Pattern Image Note
TS28: cornea epithelium Present Regionally restricted 3F' Expression was in a patch of cells at the central cornea and was absent in the peripheral cornea except for the very end.

Specimen 4A: postnatal day 21; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz (more )
Note: Double labeled: green - Pax6; red - Cdh1 (assay MGI:7397267).
Structure Level Pattern Image Note
TS28: cornea epithelium Present 4A

Specimen 4B: postnatal day 21; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz (more )
Note: Double labeled: green - Pax6; red - Cdh1 (assay MGI:7397267).
Structure Level Pattern Image Note
TS28: cornea epithelium Present 4B

Specimen 4C: postnatal day 21; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz, Tg(Aldh3a1-cre)1Zkoz/0 (more )
Note: Conditional mutant. Double labeled: green - Pax6; red - Cdh1 (assay MGI:7397267).
Structure Level Pattern Image Note
TS28: cornea epithelium Present Regionally restricted 4C Expression was in a patch of cells at the central cornea and was absent in the peripheral cornea except for the very end.

Specimen 4D: postnatal day 21; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz, Tg(Aldh3a1-cre)1Zkoz/0 (more )
Note: Conditional mutant. Double labeled: green - Pax6; red - Cdh1 (assay MGI:7397267).
Structure Level Pattern Image Note
TS28: cornea epithelium Present Regionally restricted 4D Expression was in a patch of cells at the central cornea and was absent in the peripheral cornea except for the very end.

Specimen 4E: postnatal day 21; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz (more )
Note: Double labeled with F-actin (red).
Structure Level Pattern Image Note
TS28: cornea epithelium Present 4E

Specimen 4F: postnatal day 21; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz (more )
Note: Double labeled with F-actin (red).
Structure Level Pattern Image Note
TS28: cornea epithelium Present 4F

Specimen 4G: postnatal day 21; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz, Tg(Aldh3a1-cre)1Zkoz/0 (more )
Note: Conditional mutant. Double labeled with F-actin (red).
Structure Level Pattern Image Note
TS28: cornea epithelium Present Regionally restricted 4G Expression was in a patch of cells at the central cornea and was absent in the peripheral cornea except for the very end.

Specimen 4H: postnatal day 21; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz, Tg(Aldh3a1-cre)1Zkoz/0 (more )
Note: Conditional mutant. Double labeled with F-actin (red).
Structure Level Pattern Image Note
TS28: cornea epithelium Present Regionally restricted 4H Expression was in a patch of cells at the central cornea and was absent in the peripheral cornea except for the very end.

Specimen 4I: postnatal day 21; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz (more )
Note: Double labeled: green - Pax6; red - Ctnnb1 (assay MGI:7397268).
Structure Level Pattern Image Note
TS28: cornea epithelium Present 4I

Specimen 4J: postnatal day 21; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz (more )
Note: Double labeled: green - Pax6; red - Ctnnb1 (assay MGI:7397268).
Structure Level Pattern Image Note
TS28: cornea epithelium Present 4J

Specimen 4K: postnatal day 21; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz, Tg(Aldh3a1-cre)1Zkoz/0 (more )
Note: Conditional mutant. Double labeled: green - Pax6; red - Ctnnb1 (assay MGI:7397268).
Structure Level Pattern Image Note
TS28: cornea epithelium Present Regionally restricted 4K Expression was in a patch of cells at the central cornea and was absent in the peripheral cornea except for the very end.

Specimen 4L: postnatal day 21; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz, Tg(Aldh3a1-cre)1Zkoz/0 (more )
Note: Conditional mutant. Double labeled: green - Pax6; red - Ctnnb1 (assay MGI:7397268).
Structure Level Pattern Image Note
TS28: cornea epithelium Present Regionally restricted 4L Expression was in a patch of cells at the central cornea and was absent in the peripheral cornea except for the very end.

Specimen 5A: postnatal day 2; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz (more )
Structure Level Pattern Image Note
TS27: cornea epithelium Present 5A

Specimen 5A': postnatal day 2; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz, Tg(KRT14-cre)#Smr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: cornea epithelium Present Regionally restricted 5A' Most mutants had an asymmetrical deletion pattern where one periphery had a loss of expressing cells, whereas the other periphery and conjunctiva retained expression.

Specimen 5B: postnatal day 2; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz (more )
Structure Level Pattern Image Note
TS27: cornea epithelium Present 5B

Specimen 5B': postnatal day 2; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz, Tg(KRT14-cre)#Smr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: cornea epithelium Present Regionally restricted 5B' Most mutants had an asymmetrical deletion pattern where one periphery had a loss of expressing cells, whereas the other periphery and conjunctiva retained expression.

Specimen 5C: postnatal day 2; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz (more )
Structure Level Pattern Image Note
TS27: cornea epithelium Present 5C
TS27: corneo-scleral junction Present 5C

Specimen 5C': postnatal day 2; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz, Tg(KRT14-cre)#Smr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: cornea epithelium Present Regionally restricted 5C' Most mutants had an asymmetrical deletion pattern where one periphery had a loss of expressing cells, whereas the other periphery and conjunctiva retained expression.
TS27: corneo-scleral junction Present Regionally restricted 5C' Most mutants had an asymmetrical deletion pattern where one periphery had a loss of expressing cells, whereas the other periphery and conjunctiva retained expression.

Specimen 5D: postnatal day 6; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz (more )
Structure Level Pattern Image Note
TS28: cornea epithelium Present 5D

Specimen 5D': postnatal day 6; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz, Tg(KRT14-cre)#Smr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: cornea epithelium Present Single cells 5D' There were no or few expressing cells in the central, limbal and conjunctival epithelial cells.

Specimen 5E: postnatal day 6; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz (more )
Structure Level Pattern Image Note
TS28: cornea epithelium Present 5E

Specimen 5E': postnatal day 6; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz, Tg(KRT14-cre)#Smr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: cornea epithelium Present Single cells 5E' There were no or few expressing cells in the central, limbal and conjunctival epithelial cells.

Specimen 5F: postnatal day 6; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz (more )
Structure Level Pattern Image Note
TS28: conjunctiva epithelium Present 5F
TS28: cornea epithelium Present 5F
TS28: corneo-scleral junction Present 5F

Specimen 5F': postnatal day 6; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz, Tg(KRT14-cre)#Smr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: conjunctiva epithelium Present Single cells 5F' There were no or few expressing cells in the central, limbal and conjunctival epithelial cells.
TS28: cornea epithelium Present Single cells 5F' There were no or few expressing cells in the central, limbal and conjunctival epithelial cells.
TS28: corneo-scleral junction Present Single cells 5F' There were no or few expressing cells in the central, limbal and conjunctival epithelial cells.

Specimen 6A: postnatal day 6; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz (more )
Note: Double labeled: green - Pax6; red - Krt12 (assay MGI:7397269).
Structure Level Pattern Image Note
TS28: cornea epithelium Present 6A

Specimen 6A': postnatal day 6; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz, Tg(KRT14-cre)#Smr/0 (more )
Note: Conditional mutant. Double labeled: green - Pax6; red - Krt12 (assay MGI:7397269).
Structure Level Pattern Image Note
TS28: cornea epithelium Present Single cells 6A' There were no or few expressing cells in the central cornea.

Specimen 6B: postnatal day 6; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz (more )
Note: Double labeled: green - Pax6; red - Krt12 (assay MGI:7397269).
Structure Level Pattern Image Note
TS28: conjunctiva epithelium Present 6B
TS28: cornea epithelium Present 6B
TS28: corneo-scleral junction Present 6B

Specimen 6B': postnatal day 6; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz, Tg(KRT14-cre)#Smr/0 (more )
Note: Conditional mutant. Double labeled: green - Pax6; red - Krt12 (assay MGI:7397269).
Structure Level Pattern Image Note
TS28: conjunctiva epithelium Present Single cells 6B' There were no or few expressing cells.
TS28: cornea epithelium Present Single cells 6B' There were no or few expressing cells.
TS28: corneo-scleral junction Present Single cells 6B' There were no or few expressing cells.

Specimen 6C: postnatal day 6; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz (more )
Note: Double labeled: green - Pax6; red - Krt12 (assay MGI:7397269).
Structure Level Pattern Image Note
TS28: conjunctiva epithelium Present 6C
TS28: cornea epithelium Present 6C
TS28: corneo-scleral junction Present 6C

Specimen 6C': postnatal day 6; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz, Tg(KRT14-cre)#Smr/0 (more )
Note: Conditional mutant. Double labeled: green - Pax6; red - Krt12 (assay MGI:7397269).
Structure Level Pattern Image Note
TS28: conjunctiva epithelium Present Single cells 6C' There were no or few expressing cells.
TS28: cornea epithelium Present Single cells 6C' There were no or few expressing cells.
TS28: corneo-scleral junction Present Single cells 6C' There were no or few expressing cells.

Specimen 6D: postnatal day 6; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz (more )
Note: Double labeled: green - Pax6; red - Krt14 (assay MGI:7397270).
Structure Level Pattern Image Note
TS28: cornea epithelium Present 6D

Specimen 6D': postnatal day 6; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz, Tg(KRT14-cre)#Smr/0 (more )
Note: Conditional mutant. Double labeled: green - Pax6; red - Krt14 (assay MGI:7397270).
Structure Level Pattern Image Note
TS28: cornea epithelium Present Single cells 6D' There were no or few expressing cells in the central cornea.

Specimen 6E: postnatal day 6; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz (more )
Note: Double labeled: green - Pax6; red - Krt14 (assay MGI:7397270).
Structure Level Pattern Image Note
TS28: conjunctiva epithelium Present 6E
TS28: cornea epithelium Present 6E
TS28: corneo-scleral junction Present 6E

Specimen 6E': postnatal day 6; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz, Tg(KRT14-cre)#Smr/0 (more )
Note: Conditional mutant. Double labeled: green - Pax6; red - Krt14 (assay MGI:7397270).
Structure Level Pattern Image Note
TS28: conjunctiva epithelium Present Single cells 6E' There were no or few expressing cells.
TS28: cornea epithelium Present Single cells 6E' There were no or few expressing cells.
TS28: corneo-scleral junction Present Single cells 6E' There were no or few expressing cells.

Specimen 6F: postnatal day 6; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz (more )
Note: Double labeled: green - Pax6; red - Krt14 (assay MGI:7397270).
Structure Level Pattern Image Note
TS28: conjunctiva epithelium Present 6F
TS28: cornea epithelium Present 6F
TS28: corneo-scleral junction Present 6F

Specimen 6F': postnatal day 6; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz, Tg(KRT14-cre)#Smr/0 (more )
Note: Conditional mutant. Double labeled: green - Pax6; red - Krt14 (assay MGI:7397270).
Structure Level Pattern Image Note
TS28: conjunctiva epithelium Present Single cells 6F' There were no or few expressing cells.
TS28: cornea epithelium Present Single cells 6F' There were no or few expressing cells.
TS28: corneo-scleral junction Present Single cells 6F' There were no or few expressing cells.

Specimen 6G: postnatal day 6; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz (more )
Note: Double labeled: green - Pax6; red - Krt10 (assay MGI:7397271).
Structure Level Pattern Image Note
TS28: cornea epithelium Present 6G

Specimen 6G': postnatal day 6; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz, Tg(KRT14-cre)#Smr/0 (more )
Note: Conditional mutant. Double labeled: green - Pax6; red - Krt10 (assay MGI:7397271).
Structure Level Pattern Image Note
TS28: cornea epithelium Present Single cells 6G' There were no or few expressing cells in the central cornea.

Specimen 6H: postnatal day 6; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz (more )
Note: Double labeled: green - Pax6; red - Krt10 (assay MGI:7397271).
Structure Level Pattern Image Note
TS28: conjunctiva epithelium Present 6H
TS28: cornea epithelium Present 6H
TS28: corneo-scleral junction Present 6H

Specimen 6H': postnatal day 6; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz, Tg(KRT14-cre)#Smr/0 (more )
Note: Conditional mutant. Double labeled: green - Pax6; red - Krt10 (assay MGI:7397271).
Structure Level Pattern Image Note
TS28: conjunctiva epithelium Present Single cells 6H' There were no or few expressing cells.
TS28: cornea epithelium Present Single cells 6H' There were no or few expressing cells.
TS28: corneo-scleral junction Present Single cells 6H' There were no or few expressing cells.

Specimen 6I: postnatal day 6; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz (more )
Note: Double labeled: green - Pax6; red - Krt10 (assay MGI:7397271).
Structure Level Pattern Image Note
TS28: conjunctiva epithelium Present 6I
TS28: cornea epithelium Present 6I
TS28: corneo-scleral junction Present 6I

Specimen 6I': postnatal day 6; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz, Tg(KRT14-cre)#Smr/0 (more )
Note: Conditional mutant. Double labeled: green - Pax6; red - Krt10 (assay MGI:7397271).
Structure Level Pattern Image Note
TS28: conjunctiva epithelium Present Single cells 6I' There were no or few expressing cells.
TS28: cornea epithelium Present Single cells 6I' There were no or few expressing cells.
TS28: corneo-scleral junction Present Single cells 6I' There were no or few expressing cells.

Specimen 6J: postnatal day 6; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz (more )
Note: Double labeled: green - Pax6; red - Krt4 (assay MGI:7397276).
Structure Level Pattern Image Note
TS28: cornea epithelium Present 6J

Specimen 6J': postnatal day 6; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz, Tg(KRT14-cre)#Smr/0 (more )
Note: Conditional mutant. Double labeled: green - Pax6; red - Krt4 (assay MGI:7397276).
Structure Level Pattern Image Note
TS28: cornea epithelium Present Single cells 6J' There were no or few expressing cells in the central cornea.

Specimen 6K: postnatal day 6; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz (more )
Note: Double labeled: green - Pax6; red - Krt4 (assay MGI:7397276).
Structure Level Pattern Image Note
TS28: conjunctiva epithelium Present 6K
TS28: cornea epithelium Present 6K
TS28: corneo-scleral junction Present 6K

Specimen 6K': postnatal day 6; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz, Tg(KRT14-cre)#Smr/0 (more )
Note: Conditional mutant. Double labeled: green - Pax6; red - Krt4 (assay MGI:7397276).
Structure Level Pattern Image Note
TS28: conjunctiva epithelium Present Single cells 6K' There were no or few expressing cells.
TS28: cornea epithelium Present Single cells 6K' There were no or few expressing cells.
TS28: corneo-scleral junction Present Single cells 6K' There were no or few expressing cells.

Specimen 6L: postnatal day 6; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz (more )
Note: Double labeled: green - Pax6; red - Krt4 (assay MGI:7397276).
Structure Level Pattern Image Note
TS28: conjunctiva epithelium Present 6L
TS28: cornea epithelium Present 6L
TS28: corneo-scleral junction Present 6L

Specimen 6L': postnatal day 6; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz, Tg(KRT14-cre)#Smr/0 (more )
Note: Conditional mutant. Double labeled: green - Pax6; red - Krt4 (assay MGI:7397276).
Structure Level Pattern Image Note
TS28: conjunctiva epithelium Present Single cells 6L' There were no or few expressing cells.
TS28: cornea epithelium Present Single cells 6L' There were no or few expressing cells.
TS28: corneo-scleral junction Present Single cells 6L' There were no or few expressing cells.

Specimen S1D: postnatal day 12; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz (more )
Structure Level Pattern Image Note
TS28: cornea epithelium Present S1D

Specimen S1D': postnatal day 12; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz, Tg(Aldh3a1-cre)1Zkoz/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: cornea epithelium Present Patchy S1D'

Specimen S1E: postnatal day 12; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz (more )
Structure Level Pattern Image Note
TS28: cornea epithelium Present S1E

Specimen S1E': postnatal day 12; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz, Tg(Aldh3a1-cre)1Zkoz/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: cornea epithelium Present Patchy S1E'

Specimen S3A: postnatal day 12; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz (more )
Structure Level Pattern Image Note
TS28: cornea epithelium Present S3A

Specimen S3A': postnatal day 12; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz, Tg(Aldh3a1-cre)1Zkoz/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: cornea epithelium Present Patchy S3A'

Specimen S3B: postnatal day 12; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz (more )
Structure Level Pattern Image Note
TS28: cornea epithelium Present S3B

Specimen S3B': postnatal day 12; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz, Tg(Aldh3a1-cre)1Zkoz/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: cornea epithelium Present Patchy S3B'

Specimen S3C: postnatal day 12; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz (more )
Structure Level Pattern Image Note
TS28: cornea epithelium Present S3C

Specimen S3C': postnatal day 12; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz, Tg(Aldh3a1-cre)1Zkoz/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: cornea epithelium Present Patchy S3C'

Specimen S3D: postnatal day 14; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz (more )
Structure Level Pattern Image Note
TS28: cornea epithelium Present S3D

Specimen S3D': postnatal day 14; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz, Tg(Aldh3a1-cre)1Zkoz/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: cornea epithelium Present Patchy S3D'

Specimen S3E: postnatal day 14; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz (more )
Structure Level Pattern Image Note
TS28: cornea epithelium Present S3E

Specimen S3E': postnatal day 14; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz, Tg(Aldh3a1-cre)1Zkoz/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: cornea epithelium Present Patchy S3E'

Specimen S3F: postnatal day 14; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz (more )
Structure Level Pattern Image Note
TS28: cornea epithelium Present S3F

Specimen S3F': postnatal day 14; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz, Tg(Aldh3a1-cre)1Zkoz/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: cornea epithelium Present Patchy S3F'

Specimen S4A: postnatal day 21; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz (more )
Note: Double labeled: green - Pax6; red - Casp3 (assay MGI:7397277).
Structure Level Pattern Image Note
TS28: cornea epithelium Present S4A

Specimen S4A': postnatal day 21; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz, Tg(Aldh3a1-cre)1Zkoz/0 (more )
Note: Conditional mutant. Double labeled: green - Pax6; red - Casp3 (assay MGI:7397277).
Structure Level Pattern Image Note
TS28: cornea epithelium Present Regionally restricted S4A' Expression was in a patch of cells at the central cornea (shown) and was absent in the peripheral cornea except at the very end.

Specimen S4B: postnatal day 21; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz (more )
Note: Double labeled: green - Pax6; red - Casp3 (assay MGI:7397277).
Structure Level Pattern Image Note
TS28: cornea epithelium Present S4B

Specimen S4B': postnatal day 21; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz, Tg(Aldh3a1-cre)1Zkoz/0 (more )
Note: Conditional mutant. Double labeled: green - Pax6; red - Casp3 (assay MGI:7397277).
Structure Level Pattern Image Note
TS28: cornea epithelium Present Regionally restricted S4B' Expression was in a patch of cells at the central cornea and was absent in the peripheral cornea (shown) except at the very end.

Specimen S4C: postnatal day 28; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz (more )
Note: Double labeled: green - Pax6; red - Casp3 (assay MGI:7397277).
Structure Level Pattern Image Note
TS28: cornea epithelium Present S4C

Specimen S4C': postnatal day 28; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz, Tg(Aldh3a1-cre)1Zkoz/0 (more )
Note: Conditional mutant. Double labeled: green - Pax6; red - Casp3 (assay MGI:7397277).
Structure Level Pattern Image Note
TS28: cornea epithelium Present Regionally restricted S4C' Expression was in a patch of cells at the central cornea (shown) and was absent in the peripheral cornea except at the very end.

Specimen S4D: postnatal day 28; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz (more )
Note: Double labeled: green - Pax6; red - Casp3 (assay MGI:7397277).
Structure Level Pattern Image Note
TS28: cornea epithelium Present S4D

Specimen S4D': postnatal day 28; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz, Tg(Aldh3a1-cre)1Zkoz/0 (more )
Note: Conditional mutant. Double labeled: green - Pax6; red - Casp3 (assay MGI:7397277).
Structure Level Pattern Image Note
TS28: cornea epithelium Present Regionally restricted S4D' Expression was in a patch of cells at the central cornea and was absent in the peripheral cornea (shown) except at the very end.

Specimen S5C: embryonic day 15.5; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz (more )
Structure Level Pattern Image Note
TS23: cornea epithelium Present S5C

Specimen S5C': embryonic day 15.5; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz, Tg(KRT14-cre)#Smr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: cornea epithelium Weak Patchy S5C' Expression is downregulated at presumptive conjunctival epithelial cells.

Specimen S5D: embryonic day 15.5; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz (more )
Structure Level Pattern Image Note
TS23: cornea epithelium Present S5D

Specimen S5D': embryonic day 15.5; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz, Tg(KRT14-cre)#Smr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: cornea epithelium Weak Patchy S5D' Expression is downregulated at presumptive conjunctival epithelial cells.

Specimen S5E: embryonic day 18.5; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz (more )
Structure Level Pattern Image Note
TS26: cornea epithelium Present S5E

Specimen S5E': embryonic day 18.5; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz, Tg(KRT14-cre)#Smr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: cornea epithelium Weak Patchy S5E' Expression is downregulated at presumptive conjunctival epithelial cells.

Specimen S5F: embryonic day 18.5; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz (more )
Structure Level Pattern Image Note
TS26: cornea epithelium Present S5F

Specimen S5F': embryonic day 18.5; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz, Tg(KRT14-cre)#Smr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: cornea epithelium Weak Patchy S5F' Expression is downregulated at presumptive conjunctival epithelial cells.

Specimen S7A: postnatal day 2; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz (more )
Note: Double labeled: green - Pax6; red - Krt10 (assay MGI:7397271).
Structure Level Pattern Image Note
TS27: cornea epithelium Present S7A

Specimen S7A': postnatal day 2; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz, Tg(KRT14-cre)#Smr/0 (more )
Note: Conditional mutant. Double labeled: green - Pax6; red - Krt10 (assay MGI:7397271).
Structure Level Pattern Image Note
TS27: cornea epithelium Present Patchy S7A' Most mutants had an asymmetrical deletion pattern where one periphery had a loss of expressing cells, whereas the other periphery and conjunctiva retained expression.

Specimen S7B: postnatal day 2; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz (more )
Note: Double labeled: green - Pax6; red - Krt10 (assay MGI:7397271).
Structure Level Pattern Image Note
TS27: conjunctiva epithelium Present S7B
TS27: cornea epithelium Present S7B
TS27: corneo-scleral junction Present S7B

Specimen S7B': postnatal day 2; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz, Tg(KRT14-cre)#Smr/0 (more )
Note: Conditional mutant. Double labeled: green - Pax6; red - Krt10 (assay MGI:7397271).
Structure Level Pattern Image Note
TS27: conjunctiva epithelium Present Regionally restricted S7B' Most mutants had an asymmetrical deletion pattern where one periphery had a loss of expressing cells, whereas the other periphery and conjunctiva retained expression.
TS27: cornea epithelium Present Regionally restricted S7B' Most mutants had an asymmetrical deletion pattern where one periphery had a loss of expressing cells, whereas the other periphery and conjunctiva retained expression.
TS27: corneo-scleral junction Present Regionally restricted S7B' Most mutants had an asymmetrical deletion pattern where one periphery had a loss of expressing cells, whereas the other periphery and conjunctiva retained expression.

Specimen S7C: postnatal day 2; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz (more )
Note: Double labeled: green - Pax6; red - Krt10 (assay MGI:7397271).
Structure Level Pattern Image Note
TS27: conjunctiva epithelium Present S7C
TS27: cornea epithelium Present S7C
TS27: corneo-scleral junction Present S7C

Specimen S7C': postnatal day 2; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz, Tg(KRT14-cre)#Smr/0 (more )
Note: Conditional mutant. Double labeled: green - Pax6; red - Krt10 (assay MGI:7397271).
Structure Level Pattern Image Note
TS27: conjunctiva epithelium Present S7C' Most mutants had an asymmetrical deletion pattern where one periphery had a loss of expressing cells, whereas the other periphery and conjunctiva retained expression.
TS27: cornea epithelium Present S7C' Most mutants had an asymmetrical deletion pattern where one periphery had a loss of expressing cells, whereas the other periphery and conjunctiva retained expression.
TS27: corneo-scleral junction Present S7C' Most mutants had an asymmetrical deletion pattern where one periphery had a loss of expressing cells, whereas the other periphery and conjunctiva retained expression.

Specimen S7D: postnatal day 23; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz (more )
Note: Double labeled: green - Pax6; red - Krt12 (assay MGI:7397269).
Structure Level Pattern Image Note
TS28: cornea epithelium Present S7D

Specimen S7D': postnatal day 23; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz, Tg(KRT14-cre)#Smr/0 (more )
Note: Conditional mutant. Double labeled: green - Pax6; red - Krt12 (assay MGI:7397269).
Structure Level Pattern Image Note
TS28: cornea epithelium Present Single cells S7D' There were no or few expressing cells.

Specimen S7E: postnatal day 23; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz (more )
Note: Double labeled: green - Pax6; red - Krt12 (assay MGI:7397269).
Structure Level Pattern Image Note
TS28: cornea epithelium Present S7E

Specimen S7E': postnatal day 23; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz, Tg(KRT14-cre)#Smr/0 (more )
Note: Conditional mutant. Double labeled: green - Pax6; red - Krt12 (assay MGI:7397269).
Structure Level Pattern Image Note
TS28: cornea epithelium Present Single cells S7E' There were no or few expressing cells.

Specimen S7F: postnatal day 23; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz (more )
Note: Double labeled: green - Pax6; red - Krt14 (assay MGI:7397270).
Structure Level Pattern Image Note
TS28: cornea epithelium Present S7F

Specimen S7F': postnatal day 23; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz, Tg(KRT14-cre)#Smr/0 (more )
Note: Conditional mutant. Double labeled: green - Pax6; red - Krt14 (assay MGI:7397270).
Structure Level Pattern Image Note
TS28: cornea epithelium Present Single cells S7F' There were no or few expressing cells.

Specimen S7G: postnatal day 23; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz (more )
Note: Double labeled: green - Pax6; red - Krt14 (assay MGI:7397270).
Structure Level Pattern Image Note
TS28: cornea epithelium Present S7G

Specimen S7G': postnatal day 23; Pax6tm1.1Zkoz/Pax6tm1.1Zkoz, Tg(KRT14-cre)#Smr/0 (more )
Note: Conditional mutant. Double labeled: green - Pax6; red - Krt14 (assay MGI:7397270).
Structure Level Pattern Image Note
TS28: cornea epithelium Present Single cells S7G' There were no or few expressing cells.


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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory