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Gene Expression Data
Assay Details
Assay
Reference: J:226736 Li X, et al., Concomitant inactivation of foxo3a and fancc or fancd2 reveals a two-tier protection from oxidative stress-induced hydrocephalus. Antioxid Redox Signal. 2014 Oct 20;21(12):1675-92
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7384771
Gene symbol: Cux1
Gene name: cut-like homeobox 1
Antibody: anti-Cux1/2
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Assay notes: This antibody recognizes both Cux1 and Cux2.
Results
Specimen 2B +/+: embryonic day 18.5 (more )
Note: Double labeled: brown - Cux1 and Cux2 (assay MGI:7384772); purple - Foxp2 (assay MGI:7384773).
Structure Level Pattern Image Note
TS26: cerebral cortex Present Regionally restricted 2B top left Expression is in the upper layer.
Specimen 2B Fancd2-/-: embryonic day 18.5; Fancd2tm1Hou/Fancd2tm1Hou (more )
Note: Double labeled: brown - Cux1 and Cux2 (assay MGI:7384772); purple - Foxp2 (assay MGI:7384773).
Structure Level Pattern Image Note
TS26: cerebral cortex Present Regionally restricted 2B top right Expression is in the upper layer.
Specimen 2B Foxo3a-/-: embryonic day 18.5; Foxo3tm1.1Rdp/Foxo3tm1.1Rdp (more )
Note: Double labeled: brown - Cux1 and Cux2 (assay MGI:7384772); purple - Foxp2 (assay MGI:7384773).
Structure Level Pattern Image Note
TS26: cerebral cortex Present Regionally restricted 2B bottom left Expression is in the upper layer.
Specimen 2B DKO: embryonic day 18.5; Fancd2tm1Hou/Fancd2tm1Hou, Foxo3tm1.1Rdp/Foxo3tm1.1Rdp (more )
Note: Double labeled: brown - Cux1 and Cux2 (assay MGI:7384772); purple - Foxp2 (assay MGI:7384773).
Structure Level Pattern Image Note
TS26: cerebral cortex Present 2B bottom right The upper layer was significantly reduced compared with wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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