About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:158583 Ko HW, et al., Broad-minded links cell cycle-related kinase to cilia assembly and hedgehog signal transduction. Dev Cell. 2010 Feb 16;18(2):237-47
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7380671
Gene symbol: Pax6
Gene name: paired box 6
Antibody: anti-Pax6
Detection system: Secondary antibody
Assay notes: Two antibodies were described, but the one used in this assay was not detailed. Pax6 antibody MGI:7380627 may have been used in this assay.
Results
Specimen 1A Pax6 WT: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: neural tube Present Regionally restricted 1A Pax6 WT Expression in motoneuron domain.
Specimen 1A Pax6 bromi: embryonic day 10.5; Tbc1d32bromi/Tbc1d32bromi (more )
Structure Level Pattern Image Note
TS17: neural tube Present Regionally restricted 1A Pax6 bromi Expression ectopically expanded into more ventral regions.
Specimen 2 Pax6 WT: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: neural tube Present 2_Pax6 WT
Specimen 2 Pax6 bromi: embryonic day 9.5; Tbc1d32bromi/Tbc1d32bromi (more )
Structure Level Pattern Image Note
TS15: neural tube Present 2_Pax6 bromi
Specimen 2 Pax6 Ptch1: embryonic day 9.5; Ptch1tm1Mps/Ptch1tm1Mps (more )
Structure Level Pattern Image Note
TS15: neural tube Absent 2_Pax6 Ptch1
Specimen 2 Pax6 bromi,Ptch1: embryonic day 9.5; Ptch1tm1Mps/Ptch1tm1Mps, Tbc1d32bromi/Tbc1d32bromi (more )
Structure Level Pattern Image Note
TS15: neural tube Present 2_Pax6 bromi,Ptch1 Expression pattern similar to bromi single mutant.
Specimen S2A Pax6 WT: embryonic day 9.5 (more )
Note: Double labeled: red - Pax6; green - Nkx6-1 (assay MGI:7380673).
Structure Level Pattern Image Note
TS15: neural tube Present Regionally restricted S2A (upper) WT Expression in dorsal neural tube.
Specimen S2A Pax6 bromi: embryonic day 9.5; Tbc1d32bromi/Tbc1d32bromi (more )
Note: Double labeled: red - Pax6; green - Nkx6-1 (assay MGI:7380673).
Structure Level Pattern Image Note
TS15: neural tube Present Widespread S2A (upper) bromi Expression throughout neural tube.
Specimen S2A Pax6 Prch1: embryonic day 9.5; Ptch1tm1Mps/Ptch1tm1Mps (more )
Note: Double labeled: red - Pax6; green - Nkx6-1 (assay MGI:7380673).
Structure Level Pattern Image Note
TS15: neural tube Absent S2A (upper) Ptch1
Specimen S2A Pax6 bromi,Ptch1: embryonic day 9.5; Ptch1tm1Mps/Ptch1tm1Mps, Tbc1d32bromi/Tbc1d32bromi (more )
Note: Double labeled: red - Pax6; green - Nkx6-1 (assay MGI:7380673).
Structure Level Pattern Image Note
TS15: neural tube Present Widespread S2A (upper) bromi,Ptch1 Expression throughout neural tube. Dorsal border of expression expanded dorsally compared to wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/14/2024
MGI 6.23 		The Jackson Laboratory