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Gene Expression Data
Assay Details
Assay
Reference: J:329930 Guertin TM, et al., Deciphering the role of retinoic acid in hepatic patterning and induction in the mouse. Dev Biol. 2022 Nov;491:31-42
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7378255
Gene symbol: Gata4
Gene name: GATA binding protein 4
Antibody: anti-GATA-4 (sc-9053)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 5A': embryonic day 10.5 (more )
Note: Control was either Rdh10+/+ or Rdh10trex/+. Triple labeled: green - Gata4; red - Hnf4a (assay MGI:7378252); white - Isl1 (assay MGI:7378256).
Structure Level Pattern Image Note
TS17: hepatic primordium Present Regionally restricted 5A' HNF4a-positive hepatoblasts are distributed throughout the GATA4-positive hepatic mesoderm of both the rostral lobe (blue asterisk) and the smaller caudal lobes (yellow asterisks).
TS17: septum transversum Present Regionally restricted 5A' The rostral lobe was bounded by the loosely organized Gata4-positive septum transversum mesenchyme.
Specimen 5B': embryonic day 10.5; Rdh10trex/Rdh10trex (more )
Note: Triple labeled: green - Gata4; red - Hnf4a (assay MGI:7378252); white - Isl1 (assay MGI:7378256).
Structure Level Pattern Image Note
TS17: septum transversum Present Regionally restricted 5B' The rostral liver lobe was bounded by a loosely organized Gata4-positive septum transversum mesenchyme.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
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