Kdm6b RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:323190 Guo T, et al., KDM6B interacts with TFDP1 to activate P53 signaling in regulating mouse palatogenesis. Elife. 2022 Feb 25;11:e74595
Assay type:	RNA in situ
MGI Accession ID:	MGI:7366970
Gene symbol:	Kdm6b
Gene name:	KDM1 lysine (K)-specific demethylase 6B

Results

1-S1O ©

Specimen 1-S1O: embryonic day 9.5 (more

)

Structure	Level	Pattern	Image	Note
TS15: 1st branchial arch ectoderm	Present		1-S1O	Expression in first pharyngeal arch epithelium.

1-S1P ©

Specimen 1-S1P: embryonic day 9.5; Kdm6b^tm1.1Rbo/Kdm6b^tm1.1Rbo, H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺ (more

)
Note: Conditional mutant.

Structure	Cell Type	Level	Pattern	Image	Note
TS15: 1st branchial arch ectoderm		Present		1-S1P	Expression in first pharyngeal arch epithelium.
TS15: 1st branchial arch mesenchyme derived from neural crest	migratory cranial neural crest cell	Absent		1-S1P	Expression efficiently inactivated in cranial neural crest (CNC)-derived cells.

8N ©

8O ©

Specimen 8N/O: embryonic day 13.5 (more

)
Note: Triple labeled: white - Kdm6b; green - Trp53 (assay MGI:7366973); red - TFDP1 (assay MGI:7367120).

Structure	Level	Pattern	Image	Note
TS21: palatal shelf	Present		8N , 8O	Co-expression with with Trp53 and Tfdp1.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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