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Gene Expression Data
Assay Details
Assay
Reference: J:239360 Zhang Y, et al., Dynamic expression of Lgr6 in the developing and mature mouse cochlea. Front Cell Neurosci. 2015;9:165
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7335247
Gene symbol: Sox2
Gene name: SRY (sex determining region Y)-box 2
Antibody: anti-Sox2
Detection system: Secondary antibody coupled to Cy5
Results
Specimen 1A: embryonic day 18.5; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Double labeled: red - Sox2; green - Lgr6 (assay MGI:7335244).
Structure Level Pattern Image Note
TS26: cochlear duct epithelium Present Regionally restricted 1A Expressed in the prosensory region that gives rise to the organ of Corti.
Specimen 1B E15.5 Apical: embryonic day 15.5; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Triple labeled: red - Sox2; white - Myo7a (assay MGI:7335961); green - Lgr6 (assay MGI:7335244).
Structure Level Pattern Image Note
TS23: cochlear duct epithelium Present Regionally restricted 1B-1-2 , 1B-1-4 , 1B-1-5 Expressed in the prosensory region that gives rise to the organ of Corti.
Specimen 1B E15.5 Middle: embryonic day 15.5; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Triple labeled: red - Sox2; white - Myo7a (assay MGI:7335961); green - Lgr6 (assay MGI:7335244).
Structure Level Pattern Image Note
TS23: cochlear duct epithelium Present Regionally restricted 1B-2-2 , 1B-2-4 , 1B-2-5 Expressed in the prosensory region that gives rise to the organ of Corti.
Specimen 1B E15.5 Basal: embryonic day 15.5; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Triple labeled: red - Sox2; white - Myo7a (assay MGI:7335961); green - Lgr6 (assay MGI:7335244).
Structure Level Pattern Image Note
TS23: cochlear duct epithelium Present Regionally restricted 1B-3-4 , 1B-3-5 , 1B-3-2 Expressed in the prosensory region that gives rise to the organ of Corti.
Specimen 1B E18.5 Apical: embryonic day 18.5; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Triple labeled: red - Sox2; white - Myo7a (assay MGI:7335961); green - Lgr6 (assay MGI:7335244).
Structure Cell Type Level Pattern Image Note
TS26: organ of Corti cochlear inner hair cell Present 1B-4-4 , 1B-4-5 , 1B-4-2
TS26: organ of Corti cochlear outer hair cell Present 1B-4-4 , 1B-4-5 , 1B-4-2
TS26: organ of Corti organ of Corti supporting cell Present 1B-4-4 , 1B-4-5 , 1B-4-2
TS26: cochlear duct epithelium Present Regionally restricted 1B-4-5 , 1B-4-4 , 1B-4-2 Expressed in the greater epithelium region.
Specimen 1B E18.5 Middle: embryonic day 18.5; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Triple labeled: red - Sox2; white - Myo7a (assay MGI:7335961); green - Lgr6 (assay MGI:7335244).
Structure Cell Type Level Pattern Image Note
TS26: organ of Corti cochlear inner hair cell Present 1B-5-5 , 1B-5-2 , 1B-5-4
TS26: organ of Corti cochlear outer hair cell Present 1B-5-5 , 1B-5-2 , 1B-5-4
TS26: organ of Corti organ of Corti supporting cell Present 1B-5-5 , 1B-5-2 , 1B-5-4
TS26: cochlear duct epithelium Present Regionally restricted 1B-5-2 , 1B-5-4 , 1B-5-5 Expressed in the greater epithelium region.
Specimen 1B E18.5 Basal: embryonic day 18.5; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Triple labeled: red - Sox2; white - Myo7a (assay MGI:7335961); green - Lgr6 (assay MGI:7335244).
Structure Cell Type Level Pattern Image Note
TS26: organ of Corti cochlear inner hair cell Ambiguous 1B-6-4 , 1B-6-5 , 1B-6-2 Expression was down-regulated in more differentiated hair cells in the basal region.
TS26: organ of Corti cochlear outer hair cell Ambiguous 1B-6-4 , 1B-6-5 , 1B-6-2 Expression was down-regulated in more differentiated hair cells in the basal region.
TS26: organ of Corti organ of Corti supporting cell Present 1B-6-5 , 1B-6-2 , 1B-6-4
TS26: cochlear duct epithelium Present Regionally restricted 1B-6-5 , 1B-6-4 , 1B-6-2 Expressed in the greater epithelium region.
Specimen 2A E15.5 Apical: embryonic day 15.5; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Triple labeled: red - Sox2; white - Myo7a (assay MGI:7335961); green - Lgr6 (assay MGI:7335244).
Structure Level Pattern Image Note
TS23: cochlear duct epithelium Present Regionally restricted 2A-1-4 , 2A-1-5 , 2A-1-3 Expressed in the prosensory region that gives rise to the organ of Corti.
Specimen 2A E15.5 Middle: embryonic day 15.5; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Triple labeled: red - Sox2; white - Myo7a (assay MGI:7335961); green - Lgr6 (assay MGI:7335244).
Structure Level Pattern Image Note
TS23: cochlear duct epithelium Present Regionally restricted 2A-2-3 , 2A-2-5 , 2A-2-4 Expressed in the prosensory region that gives rise to the organ of Corti.
Specimen 2A E15.5 Basal: embryonic day 15.5; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Triple labeled: red - Sox2; white - Myo7a (assay MGI:7335961); green - Lgr6 (assay MGI:7335244).
Structure Level Pattern Image Note
TS23: cochlear duct epithelium Present Regionally restricted 2A-3-4 , 2A-3-5 , 2A-3-3 Expressed in the prosensory region that gives rise to the organ of Corti.
Specimen 2A E18.5 Apical: embryonic day 18.5; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Triple labeled: red - Sox2; white - Myo7a (assay MGI:7335961); green - Lgr6 (assay MGI:7335244).
Structure Cell Type Level Pattern Image Note
TS26: cochlear duct epithelium Present Regionally restricted 2A-4-5 , 2A-4-3 , 2A-4-4 Expressed in the greater epithelium region.
TS26: organ of Corti cochlear inner hair cell Present 2A-4-3 , 2A-4-4 , 2A-4-5
TS26: organ of Corti cochlear outer hair cell Present 2A-4-3 , 2A-4-4 , 2A-4-5
TS26: organ of Corti organ of Corti supporting cell Present 2A-4-3 , 2A-4-4 , 2A-4-5
Specimen 2A E18.5 Middle: embryonic day 18.5; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Triple labeled: red - Sox2; white - Myo7a (assay MGI:7335961); green - Lgr6 (assay MGI:7335244).
Structure Cell Type Level Pattern Image Note
TS26: organ of Corti cochlear inner hair cell Present 2A-5-5 , 2A-5-3 , 2A-5-4
TS26: organ of Corti cochlear outer hair cell Present 2A-5-5 , 2A-5-3 , 2A-5-4
TS26: organ of Corti organ of Corti supporting cell Present 2A-5-5 , 2A-5-3 , 2A-5-4
TS26: cochlear duct epithelium Present Regionally restricted 2A-5-3 , 2A-5-4 , 2A-5-5 Expressed in the greater epithelium region.
Specimen 2A E18.5 Basal: embryonic day 18.5; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Triple labeled: red - Sox2; white - Myo7a (assay MGI:7335961); green - Lgr6 (assay MGI:7335244).
Structure Cell Type Level Pattern Image Note
TS26: organ of Corti cochlear inner hair cell Ambiguous 2A-6-4 , 2A-6-3 , 2A-6-5 Expression was down-regulated in more differentiated hair cells in the basal region.
TS26: organ of Corti cochlear outer hair cell Ambiguous 2A-6-4 , 2A-6-3 , 2A-6-5 Expression was down-regulated in more differentiated hair cells in the basal region.
TS26: cochlear duct epithelium Present Regionally restricted 2A-6-5 , 2A-6-4 , 2A-6-3 Expressed in the greater epithelium region.
TS26: organ of Corti organ of Corti supporting cell Present 2A-6-5 , 2A-6-3 , 2A-6-4
Specimen 3D section Apical: postnatal day 1; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Triple labeled: red - Sox2; white - Myo7a (assay MGI:7335961); green - Lgr6 (assay MGI:7335244).
Structure Cell Type Level Pattern Image Note
TS27: cochlear duct epithelium organ of Corti supporting cell Present 3D-1-4 , 3D-1-5 , 3D-1-2
Specimen 3D section Middle: postnatal day 1; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Triple labeled: red - Sox2; white - Myo7a (assay MGI:7335961); green - Lgr6 (assay MGI:7335244).
Structure Cell Type Level Pattern Image Note
TS27: cochlear duct epithelium organ of Corti supporting cell Present 3D-2-5 , 3D-2-2 , 3D-2-4
Specimen 3D section Basal: postnatal day 1; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Triple labeled: red - Sox2; white - Myo7a (assay MGI:7335961); green - Lgr6 (assay MGI:7335244).
Structure Cell Type Level Pattern Image Note
TS27: cochlear duct epithelium organ of Corti supporting cell Present 3D-3-4 , 3D-3-2 , 3D-3-5
Specimen 3D wholemount Apical: postnatal day 1; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Triple labeled: red - Sox2; white - Myo7a (assay MGI:7335961); green - Lgr6 (assay MGI:7335244).
Structure Cell Type Level Pattern Image Note
TS27: cochlear duct epithelium organ of Corti supporting cell Present 3D-4-2 , 3D-4-5 , 3D-4-4
Specimen 3D wholemount Middle: postnatal day 1; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Triple labeled: red - Sox2; white - Myo7a (assay MGI:7335961); green - Lgr6 (assay MGI:7335244).
Structure Cell Type Level Pattern Image Note
TS27: cochlear duct epithelium organ of Corti supporting cell Present 3D-5-5 , 3D-5-2 , 3D-5-4
Specimen 3D wholemount Basal: postnatal day 1; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Triple labeled: red - Sox2; white - Myo7a (assay MGI:7335961); green - Lgr6 (assay MGI:7335244).
Structure Cell Type Level Pattern Image Note
TS27: cochlear duct epithelium organ of Corti supporting cell Present 3D-6-2 , 3D-6-5 , 3D-6-4
Specimen 4 Apical P10: postnatal day 10; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Triple labeled: red - Sox2; white - Myo7a (assay MGI:7335961); green - Lgr6 (assay MGI:7335244).
Structure Cell Type Level Pattern Image Note
TS28: organ of Corti border cell of cochlea Present 4_Apical-3 , 4_Apical-2 , 4_Apical-4
TS28: organ of Corti organ of Corti supporting cell Present 4_Apical-3 , 4_Apical-2 , 4_Apical-4
Specimen 4 Apical P7: postnatal day 7; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Double labeled: red - Sox2; green - Lgr6 (assay MGI:7335244).
Structure Cell Type Level Pattern Image Note
TS28: organ of Corti organ of Corti supporting cell Present 4_Apical-6
Specimen 4 Apical P15: postnatal day 15; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Double labeled: red - Sox2; green - Lgr6 (assay MGI:7335244).
Structure Cell Type Level Pattern Image Note
TS28: organ of Corti border cell of cochlea Present 4_Apical-8
TS28: organ of Corti organ of Corti supporting cell Present 4_Apical-8
Specimen 4 Middle P10: postnatal day 10; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Triple labeled: red - Sox2; white - Myo7a (assay MGI:7335961); green - Lgr6 (assay MGI:7335244).
Structure Cell Type Level Pattern Image Note
TS28: organ of Corti border cell of cochlea Present 4_Middle-4 , 4_Middle-2 , 4_Middle-3
TS28: organ of Corti internal pillar cell of cochlea Present 4_Middle-4 , 4_Middle-2 , 4_Middle-3
TS28: organ of Corti organ of Corti supporting cell Present 4_Middle-4 , 4_Middle-2 , 4_Middle-3
Specimen 4 Middle P7: postnatal day 7; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Double labeled: red - Sox2; green - Lgr6 (assay MGI:7335244).
Structure Cell Type Level Pattern Image Note
TS28: organ of Corti border cell of cochlea Present 4_Middle-6
TS28: organ of Corti internal pillar cell of cochlea Present 4_Middle-6
TS28: organ of Corti organ of Corti supporting cell Present 4_Middle-6
Specimen 4 Middle P15: postnatal day 15; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Double labeled: red - Sox2; green - Lgr6 (assay MGI:7335244).
Structure Cell Type Level Pattern Image Note
TS28: organ of Corti border cell of cochlea Present 4_Middle-8
TS28: organ of Corti internal pillar cell of cochlea Present 4_Middle-8
TS28: organ of Corti organ of Corti supporting cell Present 4_Middle-8
Specimen 4 Basal P10: postnatal day 10; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Triple labeled: red - Sox2; white - Myo7a (assay MGI:7335961); green - Lgr6 (assay MGI:7335244).
Structure Cell Type Level Pattern Image Note
TS28: organ of Corti border cell of cochlea Present 4_Basal-2 , 4_Basal-3 , 4_Basal-4
TS28: organ of Corti internal pillar cell of cochlea Present 4_Basal-2 , 4_Basal-3 , 4_Basal-4
TS28: organ of Corti organ of Corti supporting cell Present 4_Basal-2 , 4_Basal-3 , 4_Basal-4
Specimen 4 Basal P7: postnatal day 7; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Double labeled: red - Sox2; green - Lgr6 (assay MGI:7335244).
Structure Cell Type Level Pattern Image Note
TS28: organ of Corti border cell of cochlea Present 4_Basal-6
TS28: organ of Corti internal pillar cell of cochlea Present 4_Basal-6
TS28: organ of Corti organ of Corti supporting cell Present 4_Basal-6
Specimen 4 Basal P15: postnatal day 15; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Double labeled: red - Sox2; green - Lgr6 (assay MGI:7335244).
Structure Cell Type Level Pattern Image Note
TS28: organ of Corti border cell of cochlea Present 4_Basal-8
TS28: organ of Corti internal pillar cell of cochlea Present 4_Basal-8
TS28: organ of Corti organ of Corti supporting cell Present 4_Basal-8
Specimen 5A Apical P7: postnatal day 7; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Double labeled: red - Sox2; green - Lgr6 (assay MGI:7335244).
Structure Cell Type Level Pattern Image Note
TS28: cochlear duct epithelium organ of Corti supporting cell Present 5A-1-2
Specimen 5A Apical P10: postnatal day 10; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Double labeled: red - Sox2; green - Lgr6 (assay MGI:7335244).
Structure Cell Type Level Pattern Image Note
TS28: cochlear duct epithelium organ of Corti supporting cell Present 5A-1-4
Specimen 5A Apical P15: postnatal day 15; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Double labeled: red - Sox2; green - Lgr6 (assay MGI:7335244).
Structure Cell Type Level Pattern Image Note
TS28: cochlear duct epithelium organ of Corti supporting cell Present 5A-1-6
Specimen 5A Middle P7: postnatal day 7; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Double labeled: red - Sox2; green - Lgr6 (assay MGI:7335244).
Structure Cell Type Level Pattern Image Note
TS28: cochlear duct epithelium organ of Corti supporting cell Present 5A-2-2
Specimen 5A Middle P10: postnatal day 10; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Double labeled: red - Sox2; green - Lgr6 (assay MGI:7335244).
Structure Cell Type Level Pattern Image Note
TS28: cochlear duct epithelium organ of Corti supporting cell Present 5A-2-4
Specimen 5A Middle P15: postnatal day 15; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Double labeled: red - Sox2; green - Lgr6 (assay MGI:7335244).
Structure Cell Type Level Pattern Image Note
TS28: cochlear duct epithelium organ of Corti supporting cell Present 5A-2-6
Specimen 5A Basal P7: postnatal day 7; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Double labeled: red - Sox2; green - Lgr6 (assay MGI:7335244).
Structure Cell Type Level Pattern Image Note
TS28: cochlear duct epithelium organ of Corti supporting cell Present 5A-3-2
Specimen 5A Basal P10: postnatal day 10; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Double labeled: red - Sox2; green - Lgr6 (assay MGI:7335244).
Structure Cell Type Level Pattern Image Note
TS28: cochlear duct epithelium organ of Corti supporting cell Present 5A-3-4
Specimen 5A Basal P15: postnatal day 10; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Double labeled: red - Sox2; green - Lgr6 (assay MGI:7335244).
Structure Cell Type Level Pattern Image Note
TS28: cochlear duct epithelium organ of Corti supporting cell Present 5A-3-6
Specimen 6A P20 upper: postnatal day 20; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Triple labeled: red - Sox2; white - Myo7a (assay MGI:7335961); green - Lgr6 (assay MGI:7335244).
Structure Cell Type Level Pattern Image Note
TS28: cochlear duct epithelium organ of Corti supporting cell Present 6A-1-2 , 6A-1-5 , 6A-1-4
Specimen 6A P20 lower: postnatal day 20; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Triple labeled: red - Sox2; white - Myo7a (assay MGI:7335961); green - Lgr6 (assay MGI:7335244).
Structure Cell Type Level Pattern Image Note
TS28: cochlear duct epithelium organ of Corti supporting cell Present 6A-2-5 , 6A-2-4 , 6A-2-2
Specimen 6A P30: postnatal day 30; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Triple labeled: red - Sox2; white - Myo7a (assay MGI:7335961); green - Lgr6 (assay MGI:7335244).
Structure Cell Type Level Pattern Image Note
TS28: cochlear duct epithelium organ of Corti supporting cell Present 6A-3-2 , 6A-3-4 , 6A-3-5
Specimen S1 Apical: postnatal day 3; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Triple labeled: red - Sox2; white - Myo7a (assay MGI:7335961); green - Lgr6 (assay MGI:7335244).
Structure Cell Type Level Pattern Image Note
TS27: cochlear duct epithelium organ of Corti supporting cell Present S1_Apical-5 , S1_Apical-4 , S1_Apical-2
Specimen S1 Middle: postnatal day 3; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Triple labeled: red - Sox2; white - Myo7a (assay MGI:7335961); green - Lgr6 (assay MGI:7335244).
Structure Cell Type Level Pattern Image Note
TS27: cochlear duct epithelium organ of Corti supporting cell Present S1_Middle-2 , S1_Middle-4 , S1_Middle-5
Specimen S1 Basal: postnatal day 3; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Triple labeled: red - Sox2; white - Myo7a (assay MGI:7335961); green - Lgr6 (assay MGI:7335244).
Structure Cell Type Level Pattern Image Note
TS27: cochlear duct epithelium organ of Corti supporting cell Present S1_Basal-5 , S1_Basal-4 , S1_Basal-2
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