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Gene Expression Data
Assay Details
Assay
Reference: J:308929 De Vincenti AP, et al., Lrig1 and Lrig3 cooperate to control Ret receptor signaling, sensory axonal growth and epidermal innervation. Development. 2021 Aug 15;148(16):dev197020
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7258084
Gene symbol: Prph
Gene name: peripherin
Antibody: anti-peripherin (8G2)
Detection system: Secondary antibody coupled to Cy3
Results
Specimen 4D WT: postnatal day 15 (more )
Note: Double labeled: red - Prph; green - Ret (assay MGI:7258008).
Structure Cell Type Level Pattern Image Note
TS28: lumbar dorsal root ganglion pain receptor cell Present Regionally restricted 4D Merge top , 4D Peripherin top Expression is in nociceptive neurons.

Specimen 4D Lrig1HT/Lrig3KO: postnatal day 15; Lrig3tm1.1Hhed/Lrig3tm1.1Hhed, Lrig1tm1.1Hhed/Lrig1+ (more )
Note: Double labeled: red - Prph; green - Ret (assay MGI:7258008).
Structure Cell Type Level Pattern Image Note
TS28: lumbar dorsal root ganglion pain receptor cell Present 4D Peripherin bottom , 4D Merge bottom This mutant has hypertrophic soma of Ret/Prph double-positive nonpeptidergic nociceptive neurons compared to wild-type.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory