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Gene Expression Data
Assay Details
Assay
Reference: J:304360 Dominguez-Bautista JA, et al., Programmed Cell Senescence in the Mouse Developing Spinal Cord and Notochord. Front Cell Dev Biol. 2021;9:587096
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6886042
Gene symbol: Cdkn2a
Gene name: cyclin dependent kinase inhibitor 2A
Antibody: p16 (F-12) (sc-1661)
Detection system: Secondary antibody
Results
Specimen 3A E10.5: embryonic day 10.5 (more )
Note: Double labeled: green - Cdkn2a; red - Isl1 (assay MGI:6886033).
Structure Cell Type Level Pattern Image Note
TS17: future spinal cord motor neuron Present 3A E10.5 p16 , 3A E10.5 Merge Expression in abundant cells in motoneuron zone; expression in a subpopulation of motoneurons.
Specimen 3A E12.5: embryonic day 12.5 (more )
Note: Double labeled: green - Cdkn2a; red - Isl1 (assay MGI:6886033).
Structure Cell Type Level Pattern Image Note
TS20: spinal cord motor neuron Trace 3A E12.5 p16 , 3A E12.5 Merge Number of expressing cells decreases from E10.5 to E12.5.
Specimen 3B: embryonic day 12.5 (more )
Note: Double labeled: white - Cdkn2a; blue - DAPI.
Structure Level Pattern Image Note
TS20: hand epithelium Present Regionally restricted 3B Merge , 3B p16 Expression restricted to apical ectodermal ridge.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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