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Gene Expression Data
Assay Details
Assay
Reference: J:278916 Maruyama K, et al., Isl1-expressing non-venous cell lineage contributes to cardiac lymphatic vessel development. Dev Biol. 2019 Aug 15;452(2):134-143
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6758995
Gene symbol: Adgre1
Gene name: adhesion G protein-coupled receptor E1
Antibody: Anti F4/80 (BM8)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen S5A/B: embryonic day 14.5 (more )
Note: Ventral side. Double labeled: green - Adgre1; red - Lyve1 (assay MGI:6758952).
Structure Level Pattern Image Note
TS22: arch of aorta Present Scattered S5B merge , S5A , S5B F4/80 Sparsely coexpressed with Lyve1 (likely macrophages) on the aortic wall.
Specimen S5C: embryonic day 14.5 (more )
Note: Dorsal side. Double labeled: green - Adgre1; red - Lyve1 (assay MGI:6758952).
Structure Level Pattern Image Note
TS22: heart Present Regionally restricted S5C F4/80 , S5C merge A small number of Adgre1+/Lyve1+ macrophages were identified around the sinus venosus.
Specimen S5D/E: embryonic day 14.5 (more )
Note: Double labeled: green - Adgre1; red - Lyve1 (assay MGI:6758952).
Structure Level Pattern Image Note
TS22: visceral pericardium Present S5E merge , S5E F4/80 , S5D Sparsely coexpressed with Lyve1 in macrophages.
Specimen S5F/G: embryonic day 15.5 (more )
Note: Ventral side. Double labeled: green - Adgre1; red - Lyve1 (assay MGI:6758952).
Structure Level Pattern Image Note
TS23: aorta Present Scattered S5G merge , S5F , S5G F4/80 Coexpressed with Lyve1 in macrophages.
TS23: lymphatic vessel endothelium Absent S5F , S5G F4/80 , S5G merge
Specimen S5H: embryonic day 15.5 (more )
Note: Dorsal side. Double labeled: green - Adgre1; red - Lyve1 (assay MGI:6758952).
Structure Level Pattern Image Note
TS23: visceral pericardium Present Scattered S5H merge , S5H F4/80 Coexpressed with Lyve1 in macrophages.
TS23: lymphatic vessel endothelium Absent S5H merge , S5H F4/80
Specimen S5I/J: embryonic day 15.5 (more )
Note: Double labeled: green - Adgre1; red - Lyve1 (assay MGI:6758952).
Structure Level Pattern Image Note
TS23: visceral pericardium Present Scattered S5J F4/80 , S5J merge , S5I Coexpressed with Lyve1 in macrophages.
TS23: lymphatic vessel endothelium Absent S5I , S5J F4/80 , S5J merge
Specimen S5K/L: embryonic day 16.5 (more )
Note: Ventral side. Double labeled: green - Adgre1; red - Lyve1 (assay MGI:6758952).
Structure Level Pattern Image Note
TS24: aorta Present Scattered S5L merge , S5L F4/80 , S5K Coexpressed with Lyve1 in macrophages.
TS24: lymphatic vessel endothelium Absent S5L merge , S5L F4/80 , S5K
Specimen S5M: embryonic day 16.5 (more )
Note: Dorsal side. Double labeled: green - Adgre1; red - Lyve1 (assay MGI:6758952).
Structure Level Pattern Image Note
TS24: visceral pericardium Present Scattered S5M F4/80 , S5M merge Coexpressed with Lyve1 in macrophages.
TS24: lymphatic vessel endothelium Absent S5M merge , S5M F4/80
Specimen S5N/O: embryonic day 16.5 (more )
Note: Double labeled: green - Adgre1; red - Lyve1 (assay MGI:6758952).
Structure Level Pattern Image Note
TS24: visceral pericardium Present Scattered S5O merge , S5N , S5O F4/80 Coexpressed with Lyve1 in macrophages.
TS24: lymphatic vessel endothelium Absent S5O merge , S5N , S5O F4/80
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory